One-carbon metabolism
From Proteopedia
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(New page: One-carbon metabolism refers to reactions that transfer a single carbon. Typically, these reactions are catalyzed by enzymes using vitamin-derived cofactors or prosthetic groups such a...) |
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| - | [[One-carbon metabolism]] refers to reactions that transfer a single carbon. Typically, these reactions are catalyzed by enzymes using vitamin-derived cofactors or prosthetic groups such as S-adenosyl methionine, tetrahydrofolate, cobalamin or biotin. The transfered carbon may have various oxidation states and end up as different functional groups such as methyl, methenyl, formyl, or carboxylate. One-carbon transfer reactions play a role in amino acid and nucleid acid biosynthesis, in epigenetics and cellular redox status. | + | [[One-carbon metabolism]] refers to reactions that transfer a single carbon. Typically, these reactions are catalyzed by enzymes using vitamin-derived cofactors or prosthetic groups such as S-adenosyl methionine, tetrahydrofolate, cobalamin or biotin. The transfered carbon may have various oxidation states and end up as different functional groups such as methyl, methenyl, formyl, or carboxylate. One-carbon transfer reactions play a role in amino acid and nucleid acid biosynthesis, in epigenetics and cellular redox status <ref>DOI:10.1016/j.cmet.2016.08.00</ref>. |
| + | This article is a work in process during the Spring 2022 semester. | ||
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Revision as of 21:45, 3 March 2022
One-carbon metabolism refers to reactions that transfer a single carbon. Typically, these reactions are catalyzed by enzymes using vitamin-derived cofactors or prosthetic groups such as S-adenosyl methionine, tetrahydrofolate, cobalamin or biotin. The transfered carbon may have various oxidation states and end up as different functional groups such as methyl, methenyl, formyl, or carboxylate. One-carbon transfer reactions play a role in amino acid and nucleid acid biosynthesis, in epigenetics and cellular redox status [1].
This article is a work in process during the Spring 2022 semester.
