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RNA polymerase 3D structures

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Line 202: Line 202:
*Viral DNA-dependent RNAP
*Viral DNA-dependent RNAP
-
**[[6ric]] – VvRNAP – vaccinia virus – Cryo EM<br />
+
**[[6ric]], [[7amv]], [[7aoz]], [[7ap8]], [[7ap9]], [[7aof]], [[7aoh]] – VvRNAP – vaccinia virus – Cryo EM<br />
**[[6rid]] – VvRNAP + RNA + DNA – Cryo EM<br />
**[[6rid]] – VvRNAP + RNA + DNA – Cryo EM<br />
**[[6rie]] – VvRNAP + mRNA capping enzyme + RNA + DNA – Cryo EM<br />
**[[6rie]] – VvRNAP + mRNA capping enzyme + RNA + DNA – Cryo EM<br />
Line 208: Line 208:
*Eukaryotic DNA-dependent RNAP I
*Eukaryotic DNA-dependent RNAP I
 +
**[[7oba]] – hRNAP I + TIF-IA – Cryo EM<br />
 +
**[[7obb]] – hRNAP I + DNA – Cryo EM<br />
 +
**[[7ob9]], [[7vba]], [[7vbb]], [[7vbc]] – hRNAP I in elongation complex – Cryo EM<br />
**[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br />
**[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br />
**[[2rf4]] - yRNAP I subunit RPA4<br />
**[[2rf4]] - yRNAP I subunit RPA4<br />
Line 215: Line 218:
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br />
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br />
**[[6tps]] – yRNAP I in pre-initiation complex – Cryo EM<br />
**[[6tps]] – yRNAP I in pre-initiation complex – Cryo EM<br />
 +
**[[7aoc]], [[7aod]], [[7aoe]] – fyRNAP I – fission yeast – Cryo EM<br />
*Eukaryotic DNA-dependent RNAP II
*Eukaryotic DNA-dependent RNAP II
**[[1qkl]] - hRNAP II subunit RPB6 - human<br />
**[[1qkl]] - hRNAP II subunit RPB6 - human<br />
 +
**[[7dth]] - hRNAP II subunit RPB6 - NMR<br />
**[[2c35]] - hRNAP II subunits RPB4 RPB7 (mutant) – NMR<br />
**[[2c35]] - hRNAP II subunits RPB4 RPB7 (mutant) – NMR<br />
**[[2f3i]] - hRNAP II subunits RPB8 RPB17 RPABC3 – NMR<br />
**[[2f3i]] - hRNAP II subunits RPB8 RPB17 RPABC3 – NMR<br />
**[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br />
**[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br />
**[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br />
**[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br />
 +
**[[7ozn]] – pRNAP II – Cryo EM<br />
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br />
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br />
-
**[[4x67]], [[4x6a]], [[4y52]], [[4y7n]], [[5c3e]], [[5c44]], [[5c4a]], [[5c4j]], [[5c4x]], [[6bqf]], [[6bm4]], [[6bm2]], [[6blp]], [[6blo]], [[5w51]], [[5w4u]] – yRNAP II + DNA + RNA<br />
+
**[[3j1n]], [[4v1n]], [[5fmf]], [[5x51]], [[5x50]], [[5x4z]], [[7ozo]], [[7ozp]] – yRNAP II – Cryo EM<br />
-
**[[6inq]], [[6a5u]], [[6a5t]], [[6a5r]], [[6a5p]], [[6a5o]], [[6a5l]] – yRNAP II + DNA + RNA + histones – Cryo EM<br />
+
**[[7ked]], [[7kee]], [[7kef]] – yRNAP II <br />
-
**[[3j1n]], [[4v1n]], [[5fmf]], [[5x51]], [[5x50]], [[5x4z]] – yRNAP II – Cryo EM<br />
+
**[[1y14]] - yRNAP II subunits RPB4 RPB7<br />
**[[1y14]] - yRNAP II subunits RPB4 RPB7<br />
-
**[[5flm]] – bRNAP II + DNA + RNA - bovine<br />
+
**[[3ef0]], [[3ef1]] - fyRNAP II subunit α C terminal <br />
-
**[[5oik]] – bRNAP II + SPT4 + SPT5 + DNA + RNA <br />
+
-
**[[3ef0]], [[3ef1]] - fyRNAP II subunit α C terminal – fission yeast<br />
+
**[[3h0g]] – fyRNAP II<br />
**[[3h0g]] – fyRNAP II<br />
-
**[[5u0s]] – fyRNAP II + mediator complex – Cryo EM<br />
 
*''Eukaryotic DNA-dependent RNAP II complex with DNA/RNA''
*''Eukaryotic DNA-dependent RNAP II complex with DNA/RNA''
**[[4boc]] – hRNAP + DNA<br />
**[[4boc]] – hRNAP + DNA<br />
 +
**[[5flm]] – bRNAP II +in elongation complex - bovine<br />
 +
**[[5oik]] – bRNAP II + SPT4 + SPT5 + DNA + RNA <br />
**[[1i6h]], [[4a3i]] - yRNAP II + DNA<br />
**[[1i6h]], [[4a3i]] - yRNAP II + DNA<br />
**[[4v1m]] - yRNAP II + DNA – Cryo EM<br />
**[[4v1m]] - yRNAP II + DNA – Cryo EM<br />
-
**[[1r9s]], [[2ja5]], [[2ja6]], [[2ja7]], [[2ja8]], [[2nvq]], [[2nvt]], [[2nvx]], [[2nvy]], [[2nvz]], [[3gtg]], [[3gtj]], [[3gtk]], [[3gtl]], [[3gtm]], [[3gto]], [[3gtp]], [[3gtq]], [[3hov]], [[3how]], [[3hox]], [[3hoy]], [[3hoz]], [[3po2]], [[3po3]], [[3m3y]], [[3m4o]], [[4a3g]], [[4a93]], [[4a3b]], [[4a3c]], [[4a3d]], [[4a3e]], [[4a3f]], [[4a3j]], [[4a3k]], [[4a3l]], [[4a3m]] - yRNAP II + RNA + DNA<br />
+
**[[1r9s]], [[2ja5]], [[2ja6]], [[2ja7]], [[2ja8]], [[2nvq]], [[2nvt]], [[2nvx]], [[2nvy]], [[2nvz]], [[3gtg]], [[3gtj]], [[3gtk]], [[3gtl]], [[3gtm]], [[3gto]], [[3gtp]], [[3gtq]], [[3hov]], [[3how]], [[3hox]], [[3hoy]], [[3hoz]], [[3po2]], [[3po3]], [[3m3y]], [[3m4o]], [[4a3g]], [[4a93]], [[4a3b]], [[4a3c]], [[4a3d]], [[4a3e]], [[4a3f]], [[4a3j]], [[4a3k]], [[4a3l]], [[4a3m]], [[4x67]], [[4x6a]], [[4y52]], [[4y7n]], [[5c3e]], [[5c44]], [[5c4a]], [[5c4j]], [[5c4x]], [[6bqf]], [[6bm4]], [[6bm2]], [[6blp]], [[6blo]], [[5w51]], [[5w4u]] - yRNAP II + RNA + DNA<br />
**[[5vvs]] - yRNAP II + RNA + DNA – Cryo EM<br />
**[[5vvs]] - yRNAP II + RNA + DNA – Cryo EM<br />
**[[1y1w]], [[1y77]], [[2r7z]], [[2r92]], [[2r93]], [[3h3v]], [[3rzd]], [[3rzo]], [[3s15]], [[3s16]], [[3s17]], [[3s1m]], [[3s1n]], [[3s1q]], [[3s1r]], [[3s2d]], [[3s2h]] - yRNAP II + RNA
**[[1y1w]], [[1y77]], [[2r7z]], [[2r92]], [[2r93]], [[3h3v]], [[3rzd]], [[3rzo]], [[3s15]], [[3s16]], [[3s17]], [[3s1m]], [[3s1n]], [[3s1q]], [[3s1r]], [[3s2d]], [[3s2h]] - yRNAP II + RNA
Line 251: Line 255:
**[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br />
**[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br />
**[[3j0k]], [[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hRNAP II + TFIIF – Cryo EM <br />
**[[3j0k]], [[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hRNAP II + TFIIF – Cryo EM <br />
 +
**[[6xre]] – hRNAP II + p53 – Cryo EM <br />
**[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br />
**[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br />
 +
[[7nvu]], [[7nvt]], [[7nvu]] - pRNAP II + DNA + TFIIA + TFIIF + TATA-box-binding protein – pig - Cryo EM<br />
 +
**[[7edx]], [[7eg7]], [[7eg8]], [[7eg9]], [[7ega]], [[7egb]], [[7egc]] - pRNAP II + DNA + TFIIA + TFIIB + TFIIE + TFIIF + TATA-box-binding protein - Cryo EM<br />
 +
**[[7nw0]] - pRNAP II + DNA + TFIIB + TFIIH + MAT1 + TATA-box-binding protein - Cryo EM<br />
 +
**[[7okx]], [[7oky]] – pRNAP II + RNA + DNA + SPT5 + ELL2 – Cryo EM<br />
 +
**[[7ol0]] – pRNAP II + RNA + DNA + SPT5 – Cryo EM<br />
 +
**[[7oo3]] – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM<br />
 +
**[[7oop]], [[7opc]], [[7opd]] – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM<br />
 +
**[[7oob]] – pRNAP II + RNA + CSA + CSB + SPT6 + UVSSA + PAF – Cryo EM<br />
 +
**[[6gml]] – pRNAP II + RNA + DNA + DSIF + NELF – Cryo EM<br />
 +
**[[6gmh]], [[6ted]] – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM<br />
 +
**[[6exv]] – pRNAP II + RNA + DNA + amatoxin – Cryo EM<br />
 +
**[[7b7u]], [[7f4g]] – pRNAP II + hRPAP2 – Cryo EM<br />
 +
**[[7nvy]], [[7nvz]] – pRNAP II in pre-initiation complex – Cryo EM<br />
 +
**[[7nvr]] – pRNAP II in pre-initiation complex + hmediator – Cryo EM<br />
 +
**[[7b0y]] – pRNAP II in transcription complex + U1 SNRNP – Cryo EM<br />
**[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br />
**[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br />
**[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br />
**[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br />
Line 259: Line 279:
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
-
**[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]] - yRNAP II in elongation complex<br />
+
**[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]], [[7rim]], [[7rip]], [[7riq]] [[7riw]], [[7rix]], [[7riy]] - yRNAP II in elongation complex<br />
-
**[[6gml]] – pRNAP II + RNA + DNA + DSIF + NELF – pig – Cryo EM<br />
+
**[[6a5v]], [[6a5u]], [[6a5t]], [[6a5r]], [[6a5p]], [[6a5o]], [[6a5l]], [[7nkx]], [[7nky]] – yRNAP II + DNA + RNA + histones – Cryo EM<br />
-
**[[6gmh]], [[6ted]] – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM<br />
+
**[[7ml0]], [[7ml1]], [[7ml2]], [[7ml4]], [[7o4i]], [[7o4j]], [[7o4k]], [[7o4l]], [[7o72]], [[7o73]], [[7o75]] - yRNAP II + DNA + TFIIH + TATA-box-binding protein – Cryo EM<br />
-
**[[6exv]] – pRNAP II + RNA + DNA + amatoxin – Cryo EM<br />
+
*''Eukaryotic DNA-dependent RNAP II complex with small molecule''
*''Eukaryotic DNA-dependent RNAP II complex with small molecule''

Revision as of 10:34, 8 March 2022

Updated on 08-March-2022 - For a general description of the protein see RNA polymerase

7nvu, 7nvt, 7nvu - pRNAP II + DNA + TFIIA + TFIIF + TATA-box-binding protein – pig - Cryo EM



Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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