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2pcr
From Proteopedia
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| - | [[Image:2pcr.jpg|left|200px]] | ||
| - | + | ==Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5== | |
| - | + | <StructureSection load='2pcr' size='340' side='right'caption='[[2pcr]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2pcr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCR FirstGlance]. <br> | |
| - | | | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | | | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Inositol-phosphate_phosphatase Inositol-phosphate phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.25 3.1.3.25] </span></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcr OCA], [https://pdbe.org/2pcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcr RCSB], [https://www.ebi.ac.uk/pdbsum/2pcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcr TOPSAN]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BSUHB_AQUAE BSUHB_AQUAE]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1-phosphate (I-1-P). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]] | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | + | [[Category: Aquae]] | |
| - | [[Category: | + | |
[[Category: Inositol-phosphate phosphatase]] | [[Category: Inositol-phosphate phosphatase]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Agari, Y | + | [[Category: Agari, Y]] |
| - | [[Category: Antonyuk, S V | + | [[Category: Antonyuk, S V]] |
| - | [[Category: Bessho, Y | + | [[Category: Bessho, Y]] |
| - | [[Category: Ebihara, A | + | [[Category: Ebihara, A]] |
| - | [[Category: Ellis, M J | + | [[Category: Ellis, M J]] |
| - | [[Category: Gayathri, D | + | [[Category: Gayathri, D]] |
| - | [[Category: Hasnain, S S | + | [[Category: Hasnain, S S]] |
| - | [[Category: Jeyakanthan, J | + | [[Category: Jeyakanthan, J]] |
| - | [[Category: Kuramitsu, S | + | [[Category: Kuramitsu, S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Shinkai, A | + | [[Category: Shinkai, A]] |
| - | [[Category: Shiro, Y | + | [[Category: Shiro, Y]] |
| - | [[Category: Strange, R W | + | [[Category: Strange, R W]] |
| - | [[Category: Velmurugan, D | + | [[Category: Velmurugan, D]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
| - | [[Category: | + | [[Category: Bipolar disorder]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | [[Category: | + | [[Category: National project on protein structural and functional analyse]] |
| - | + | [[Category: Nppsfa]] | |
| - | [[Category: | + | [[Category: Rsgi]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5
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Categories: Aquae | Inositol-phosphate phosphatase | Large Structures | Agari, Y | Antonyuk, S V | Bessho, Y | Ebihara, A | Ellis, M J | Gayathri, D | Hasnain, S S | Jeyakanthan, J | Kuramitsu, S | Structural genomic | Shinkai, A | Shiro, Y | Strange, R W | Velmurugan, D | Yokoyama, S | Bipolar disorder | Hydrolase | National project on protein structural and functional analyse | Nppsfa | Rsgi
