This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3geu
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3geu.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of IcaR from Staphylococcus aureus, a member of the tetracycline repressor protein family== | |
| - | + | <StructureSection load='3geu' size='340' side='right'caption='[[3geu]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3geu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">icaR, SACOL2688 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3geu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3geu OCA], [https://pdbe.org/3geu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3geu RCSB], [https://www.ebi.ac.uk/pdbsum/3geu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3geu ProSAT], [https://www.topsan.org/Proteins/CSGID/3geu TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/ICAR_STAAC ICAR_STAAC]] Represses transcription of the icaADBC operon necessary for biofilm production. | |
| - | == | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [[Category: | + | Check<jmol> |
| - | [[Category: Anderson, S M | + | <jmolCheckbox> |
| - | [[Category: Anderson, W F | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3geu_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Brunzelle, J S | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Papazisi, L | + | </jmolCheckbox> |
| - | [[Category: Savchenko, A | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3geu ConSurf]. |
| - | [[Category: Skarina, T | + | <div style="clear:both"></div> |
| - | [[Category: Wawrzak, Z | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staac]] | ||
| + | [[Category: Anderson, S M]] | ||
| + | [[Category: Anderson, W F]] | ||
| + | [[Category: Brunzelle, J S]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Papazisi, L]] | ||
| + | [[Category: Savchenko, A]] | ||
| + | [[Category: Skarina, T]] | ||
| + | [[Category: Wawrzak, Z]] | ||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
| Line 31: | Line 39: | ||
[[Category: Intercellular adhesion regulator]] | [[Category: Intercellular adhesion regulator]] | ||
[[Category: Repressor]] | [[Category: Repressor]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Tetr family]] | [[Category: Tetr family]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 11:29:23 2009'' | ||
Current revision
Crystal Structure of IcaR from Staphylococcus aureus, a member of the tetracycline repressor protein family
| |||||||||||
Categories: Large Structures | Staac | Anderson, S M | Anderson, W F | Brunzelle, J S | Structural genomic | Papazisi, L | Savchenko, A | Skarina, T | Wawrzak, Z | Cell adhesion | Csgid | Dna-binding | Idp00851 | Intercellular adhesion regulator | Repressor | Tetr family | Transcription | Transcription regulation

