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Revision as of 20:19, 15 March 2022

Metabotropic Glutamate Receptor / mGlu Receptor 1

spinqualitylabelsall models Metabotropic Glutamate Receptor 5 PDB:4oo9 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Figure 1. The coolest image of this protein EVAH!!! Metabotropic glutamate receptor [1] [2] Contents 1 Introduction 1.1 Relevance 1.2 Function 2 Structure 2.1 Chains 2.1.1 Domains 2.2 Conformational Changes 3 Clinical Relevance 3.1 Role 3.2 Disease Introduction Relevance Function [1] [2] Structure Chains Domains Conformational Changes Clinical Relevance Role Disease

References

1. ↑ ^{1.0 1.1} Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
2. ↑ ^{2.0 2.1} Seven AB, Barros-Alvarez X, de Lapeyriere M, Papasergi-Scott MM, Robertson MJ, Zhang C, Nwokonko RM, Gao Y, Meyerowitz JG, Rocher JP, Schelshorn D, Kobilka BK, Mathiesen JM, Skiniotis G. G-protein activation by a metabotropic glutamate receptor. Nature. 2021 Jun 30. pii: 10.1038/s41586-021-03680-3. doi:, 10.1038/s41586-021-03680-3. PMID:34194039 doi:http://dx.doi.org/10.1038/s41586-021-03680-3

Student Contributors

• Courtney Vennekotter
• Cade Chezem