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2rpz
From Proteopedia
(Difference between revisions)
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<StructureSection load='2rpz' size='340' side='right'caption='[[2rpz]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2rpz' size='340' side='right'caption='[[2rpz]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rpz]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rpz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RPZ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rpz OCA], [https://pdbe.org/2rpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rpz RCSB], [https://www.ebi.ac.uk/pdbsum/2rpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rpz ProSAT], [https://www.topsan.org/Proteins/RSGI/2rpz TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ABEC2_MOUSE ABEC2_MOUSE]] Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 06:55, 16 March 2022
Solution structure of the monomeric form of mouse APOBEC2
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Categories: Large Structures | Lk3 transgenic mice | Hayashi, F | Inoue, M | Kigawa, T | Muto, Y | Nagashima, T | Nagata, T | Structural genomic | Yokoyama, S | Cytidine deaminase | Hydrolase | Metal-binding | Mrna processing | National project on protein structural and functional analyse | Nppsfa | Rsgi | Zinc
