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3gyg

From Proteopedia

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{{Seed}}
 
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[[Image:3gyg.png|left|200px]]
 
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==Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis==
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The line below this paragraph, containing "STRUCTURE_3gyg", creates the "Structure Box" on the page.
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<StructureSection load='3gyg' size='340' side='right'caption='[[3gyg]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3gyg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GYG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3gyg| PDB=3gyg | SCENE= }}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ntdB, yhjK, BSU10540 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyg OCA], [https://pdbe.org/3gyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gyg RCSB], [https://www.ebi.ac.uk/pdbsum/3gyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyg ProSAT], [https://www.topsan.org/Proteins/MCSG/3gyg TOPSAN]</span></td></tr>
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===Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis===
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/NTDB_BACSU NTDB_BACSU]] Involved in the biosynthesis of kanosamine (3-amino-3-deoxy-D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6-phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate.<ref>PMID:14612444</ref> <ref>PMID:23586652</ref>
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==About this Structure==
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== Evolutionary Conservation ==
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3GYG is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYG OCA].
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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Check<jmol>
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[[Category: Jedrzejczak, R.]]
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<jmolCheckbox>
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[[Category: Joachimiak, A.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyg_consurf.spt"</scriptWhenChecked>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Nocek, B.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Stein, A.]]
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</jmolCheckbox>
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[[Category: Wu, R.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gyg ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Bacsu]]
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[[Category: Large Structures]]
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[[Category: Jedrzejczak, R]]
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[[Category: Joachimiak, A]]
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[[Category: Structural genomic]]
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[[Category: Nocek, B]]
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[[Category: Stein, A]]
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[[Category: Wu, R]]
[[Category: Antibiotic biosynthesis]]
[[Category: Antibiotic biosynthesis]]
[[Category: Haloacid dehalogenase-like hydrolase]]
[[Category: Haloacid dehalogenase-like hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Pf05116]]
[[Category: Pf05116]]
[[Category: Pf08282]]
[[Category: Pf08282]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 5 09:05:07 2009''
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Current revision

Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis

PDB ID 3gyg

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OCA

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