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2w0n

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==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==
==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==
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<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2w0n' size='340' side='right'caption='[[2w0n]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ojg|1ojg]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ojg|1ojg]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [https://pdbe.org/2w0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [https://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
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[[https://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
[[Category: Histidine kinase]]
[[Category: Histidine kinase]]
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[[Category: Large Structures]]
[[Category: Baldus, M]]
[[Category: Baldus, M]]
[[Category: Becker, S]]
[[Category: Becker, S]]

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Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS

PDB ID 2w0n

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