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Sigma factor 3D structures

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*E. coli sigma factor complex with protein, DNA and RNA
*E. coli sigma factor complex with protein, DNA and RNA
-
**[[6p1k]] – EcSF-70 + EcRNAP subunits α,β,β’,ω - Cryo EM<br />
+
**[[6p1k]], [[7khb]] – EcSF-70 + EcRNAP subunits α,β,β’,ω - Cryo EM<br />
**[[6vjs]] – EcSF-70 + EcRNAP subunits α,β,β’,ω <br />
**[[6vjs]] – EcSF-70 + EcRNAP subunits α,β,β’,ω <br />
**[[3iyd]] – EcSF-70 in transcription initiation complex + catabolite gene activator<br />
**[[3iyd]] – EcSF-70 in transcription initiation complex + catabolite gene activator<br />
**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />
**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />
-
**[[4yln]], [[4ylo]], [[4ylp]], [[6n62]] – EcSF-70 in transcription initiation complex<br />
+
**[[7khe]], [[7khi]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P – Cryo EM<br />
-
**[[6b6h]] – EcSF-70 in transcription activation complex - Cryo EM<br />
+
**[[7khc]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + POP – Cryo EM<br />
 +
**[[4yln]], [[4ylo]], [[4ylp]], [[6n62]], [[6utv]], [[6utw]], [[6utx]] [[6uty]], [[6utz]], [[6uu0]], [[6uu1]], [[6uuc]] [[6uu3]], [[6uu4]], [[6uu5]], [[6uu6]], [[6uu7]], [[6uu8]], [[6uu2]], [[6uua]], [[6uuc]] – EcSF-70 in transcription initiation complex<br />
 +
**[[6b6h]], [[6xl5]], [[6xl9]], [[6xlj]], [[6xll]] – EcSF-70 in transcription activation complex - Cryo EM<br />
**[[5nss]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM<br />
**[[5nss]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM<br />
**[[5nsr]], [[6gh6]], [[6gh5]], [[6gfw]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
**[[5nsr]], [[6gh6]], [[6gh5]], [[6gfw]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
 +
**[[7bef]], [[7beg]], [[7chw]], [[7mkd]], [[7mke]], [[7mki]], [[7mkj]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
**[[6n61]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA<br />
**[[6n61]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA<br />
**[[6n60]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA<br />
**[[6n60]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA<br />
Line 100: Line 103:
**[[5vt0]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM<br />
**[[5vt0]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM<br />
**[[6k4y]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM<br />
**[[6k4y]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM<br />
-
**[[6ldi]], [[7c17]] – EcSF-70 in transcription activation complex + Cuer – Cryo EM<br />
+
**[[6ldi]], [[6xh7]], [[6xh8]], [[7c17]] – EcSF-70 in transcription activation complex + Cuer – Cryo EM<br />
**[[6pb4]], [[6pb5]], [[6pb6]] – EcSF-70 in transcription activation complex + Crp – Cryo EM<br />
**[[6pb4]], [[6pb5]], [[6pb6]] – EcSF-70 in transcription activation complex + Crp – Cryo EM<br />
**[[6n57]], [[6n58]] – EcSF-70 in transcription initiation complex + Tsar – Cryo EM<br />
**[[6n57]], [[6n58]] – EcSF-70 in transcription initiation complex + Tsar – Cryo EM<br />
Line 107: Line 110:
**[[7khe]] – EcSF-70 in transcription initiation complex + GTP – Cryo EM<br />
**[[7khe]] – EcSF-70 in transcription initiation complex + GTP – Cryo EM<br />
**[[7chw]], [[7khb]] – EcSF-70 in transcription open promoter complex – Cryo EM<br />
**[[7chw]], [[7khb]] – EcSF-70 in transcription open promoter complex – Cryo EM<br />
-
**[[7c97]] – EcSF-70 in transcription open promoter complex + SSPA – Cryo EM<br />
+
**[[6wmu]], [[7c97]], [[7dy6]] – EcSF-70 in transcription open promoter complex + SspA – Cryo EM<br />
**[[7khi]] – EcSF-70 in transcription open promoter complex + DKSA + G4P – Cryo EM<br />
**[[7khi]] – EcSF-70 in transcription open promoter complex + DKSA + G4P – Cryo EM<br />
**[[7khc]] – EcSF-70 in transcription closed promoter complex – Cryo EM<br />
**[[7khc]] – EcSF-70 in transcription closed promoter complex – Cryo EM<br />
 +
**[[6xlm]] – EcSF-70 in elongation complex – Cryo EM<br />
**[[6pmi]], [[6pmj]] – EcSF-28 in transcription initiation complex – Cryo EM<br />
**[[6pmi]], [[6pmj]] – EcSF-28 in transcription initiation complex – Cryo EM<br />
**[[5ipl]], [[5ipm]], [[5ipn]] – EcSF-38 in transcription initiation complex <br />
**[[5ipl]], [[5ipm]], [[5ipn]] – EcSF-38 in transcription initiation complex <br />
Line 115: Line 119:
*Other sigma factor complex with protein, DNA and RNA
*Other sigma factor complex with protein, DNA and RNA
-
**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]], [[6p71]], [[6p70]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]] – TtSF-A in reiterative transcription complex <br />
+
**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]], [[6p71]], [[6p70]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[7mli]], [[7mlj]] – TtSF-A in reiterative transcription complex <br />
 +
**[[7rdq]] – TtSF-A in reiterative transcription complex – Cryo EM<br />
**[[5vo8]] – TtSF-A in reiterative transcription complex + GTP<br />
**[[5vo8]] – TtSF-A in reiterative transcription complex + GTP<br />
**[[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]], [[6lts]], [[5e17]], [[5e18]] – TtSF-A in initial transcription complex <br />
**[[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]], [[6lts]], [[5e17]], [[5e18]] – TtSF-A in initial transcription complex <br />
Line 121: Line 126:
**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />
**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />
**[[5voi]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA <br />
**[[5voi]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA <br />
 +
**[[7eh2]], [[7mlb]] – TtSF-A in transcription initiation complex <br />
**[[5d4c]] – TtSF-A in transcription initiation complex + CTP + ATP<br />
**[[5d4c]] – TtSF-A in transcription initiation complex + CTP + ATP<br />
**[[5d4d]] – TtSF-A in transcription initiation complex + CTP + NAD<br />
**[[5d4d]] – TtSF-A in transcription initiation complex + CTP + NAD<br />
**[[5d4e]] – TtSF-A in transcription initiation complex + CTP + dephosphate-CoA<br />
**[[5d4e]] – TtSF-A in transcription initiation complex + CTP + dephosphate-CoA<br />
-
**[[5x22]] – TtSF-A in transcription initiation complex + CMPPP<br />
+
**[[5x22]], [[7eh0]], [[7eh1]] – TtSF-A in transcription initiation complex + CMPPP<br />
**[[5i2d]] – TtSF-A in transcription activation complex + transcriptional regulator <br />
**[[5i2d]] – TtSF-A in transcription activation complex + transcriptional regulator <br />
 +
**[[7f75]] – BsSF-A in transcription activation complex + transcriptional regulator – Cryo EM<br />
 +
**[[7ckq]] – BsSF-A in transcription activation complex + multidrug regulator + YKZG – Cryo EM<br />
**[[3n97]] – TaSF-A region 4 + RNAP subunits α + DNA<br />
**[[3n97]] – TaSF-A region 4 + RNAP subunits α + DNA<br />
**[[4xln]], [[4xlp]], [[4xlq]], [[5tjg]] – TaSF-A in transcription initiation complex<br />
**[[4xln]], [[4xlp]], [[4xlq]], [[5tjg]] – TaSF-A in transcription initiation complex<br />
Line 132: Line 140:
**[[1rio]] - TaSF-A region 4 + repression protein CI + DNA<br />
**[[1rio]] - TaSF-A region 4 + repression protein CI + DNA<br />
**[[6dcf]] – MtSF-A in transcription initiation complex + RBPA<br />
**[[6dcf]] – MtSF-A in transcription initiation complex + RBPA<br />
-
**[[5uha]], [[5uh5]], [[5uh8]], [[5uh9]] – MtSF-A in transcription initiation complex<br />
+
**[[5uha]], [[5uh5]], [[5uh8]], [[5uh9]], [[7rwi]] – MtSF-A in transcription initiation complex<br />
-
**[[6c04]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM<br />
+
**[[6dcf]] – MtSF-A in transcription initiation complex + RbpA<br />
 +
**[[6c04]], [[7kin]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM<br />
 +
**[[7kif]], [[7kim]] – MtSF-A + RNAP subunits α,β,β’,ω + WhiB7 + DNA - Cryo EM<br />
**[[5uhe]], [[5uhf]] – MtSF-A in transcription initiation complex + inhibitor<br />
**[[5uhe]], [[5uhf]] – MtSF-A in transcription initiation complex + inhibitor<br />
**[[6jcy]], [[6jcx]], [[5zx2]] – MtSF-H in transcription initiation complex<br />
**[[6jcy]], [[6jcx]], [[5zx2]] – MtSF-H in transcription initiation complex<br />
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**[[5tw1]], [[6cce]] – MsSF-A in transcription initiation complex + peptide - ''Mycobacterium smegmatis''<br />
**[[5tw1]], [[6cce]] – MsSF-A in transcription initiation complex + peptide - ''Mycobacterium smegmatis''<br />
**[[5vi5]], [[5vi8]], [[6vvv]] – MsSF-A in transcription initiation complex<br />
**[[5vi5]], [[5vi8]], [[6vvv]] – MsSF-A in transcription initiation complex<br />
-
**[[6ccv]] – MsSF-A in transcription initiation complex + peptide + RbpA + antibiotic<br />
+
**[[7p5x]] – MsSF-A in transcription initiation complex + PafBC – Cryo EM<br />
 +
**[[7l7b]] – SF-A + RNAP subunits α,β,β’,ω + antibiotic – Clostridia bacterium - Cryo EM<br />
*Sigma factor complex with protein and DNA and antibiotics
*Sigma factor complex with protein and DNA and antibiotics
Line 150: Line 161:
**[[5uh6]], [[5uhc]], [[5uhd]], [[5uhb]] – MtSF-A in transcription initiation complex + antibiotic<br />
**[[5uh6]], [[5uhc]], [[5uhd]], [[5uhb]] – MtSF-A in transcription initiation complex + antibiotic<br />
**[[6bzo]] – MtSF-A in transcription initiation complex + RbpA + antibiotic - Cryo EM<br />
**[[6bzo]] – MtSF-A in transcription initiation complex + RbpA + antibiotic - Cryo EM<br />
-
**[[6vvx]], [[6vvz]] – MtSF-A in transcription initiation complex + antibiotic – Cryo EM<br />
+
**[[6ccv]] – MsSF-A in transcription initiation complex + peptide + RbpA + antibiotic<br />
 +
**[[6vvt]], [[6vvx]], [[6vvz]] – MtSF-A in transcription initiation complex + antibiotic – Cryo EM<br />
**[[6vvy]], [[6vw0]] – MtSF-A in transcription open promoter complex + antibiotic – Cryo EM<br />
**[[6vvy]], [[6vw0]] – MtSF-A in transcription open promoter complex + antibiotic – Cryo EM<br />
**[[6m7j]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA + antibiotic – Cryo EM<br />
**[[6m7j]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA + antibiotic – Cryo EM<br />

Revision as of 07:50, 6 April 2022

3D structures of sigma factor

Updated on 06-April-2022

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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