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2wfd
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2wfd' size='340' side='right' caption='[[2wfd]], [[Resolution|resolution]] 3.25Å' scene=''> | + | ==Structure of the human cytosolic leucyl-tRNA synthetase editing domain== |
| + | <StructureSection load='2wfd' size='340' side='right'caption='[[2wfd]], [[Resolution|resolution]] 3.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wfd]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wfd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WFD FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Leucine--tRNA_ligase Leucine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.4 6.1.1.4] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfd OCA], [https://pdbe.org/2wfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfd RCSB], [https://www.ebi.ac.uk/pdbsum/2wfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfd ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/2wfd_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/2wfd_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wfd ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2wfd" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Aminoacyl tRNA | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
| + | [[Category: Large Structures]] | ||
[[Category: Leucine--tRNA ligase]] | [[Category: Leucine--tRNA ligase]] | ||
| - | [[Category: Alley, M R.K | + | [[Category: Alley, M R.K]] |
| - | [[Category: Baker, S J | + | [[Category: Baker, S J]] |
| - | [[Category: Cusack, S | + | [[Category: Cusack, S]] |
| - | [[Category: Hernandez, V | + | [[Category: Hernandez, V]] |
| - | [[Category: Mao, W | + | [[Category: Mao, W]] |
| - | [[Category: Plattner, J J | + | [[Category: Plattner, J J]] |
| - | [[Category: Seiradake, E | + | [[Category: Seiradake, E]] |
[[Category: Aminoacyl-trna synthetase]] | [[Category: Aminoacyl-trna synthetase]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| + | [[Category: Cytoplasm]] | ||
[[Category: Editing domain]] | [[Category: Editing domain]] | ||
| - | [[Category: Human]] | ||
[[Category: Hydrolysis of mis-charged trna]] | [[Category: Hydrolysis of mis-charged trna]] | ||
[[Category: Leucyl-trna synthetase]] | [[Category: Leucyl-trna synthetase]] | ||
| Line 50: | Line 53: | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Protein biosynthesis]] | [[Category: Protein biosynthesis]] | ||
Current revision
Structure of the human cytosolic leucyl-tRNA synthetase editing domain
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Categories: Human | Large Structures | Leucine--tRNA ligase | Alley, M R.K | Baker, S J | Cusack, S | Hernandez, V | Mao, W | Plattner, J J | Seiradake, E | Aminoacyl-trna synthetase | Atp-binding | Cytoplasm | Editing domain | Hydrolysis of mis-charged trna | Leucyl-trna synthetase | Ligase | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein biosynthesis
