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3iqt
From Proteopedia
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| - | {{STRUCTURE_3iqt| PDB=3iqt | SCENE= }} | ||
| - | ===Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.=== | ||
| - | == | + | ==Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.== |
| - | [[http://www.uniprot.org/uniprot/BARA_ECOL6 BARA_ECOL6]] Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity). | + | <StructureSection load='3iqt' size='340' side='right'caption='[[3iqt]], [[Resolution|resolution]] 1.40Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3iqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecol6 Ecol6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IQT FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">barA, c3349 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iqt OCA], [https://pdbe.org/3iqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iqt RCSB], [https://www.ebi.ac.uk/pdbsum/3iqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iqt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BARA_ECOL6 BARA_ECOL6]] Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/3iqt_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iqt ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ecol6]] | ||
[[Category: Histidine kinase]] | [[Category: Histidine kinase]] | ||
| - | [[Category: Cuff, M E | + | [[Category: Large Structures]] |
| - | [[Category: Freeman, L | + | [[Category: Cuff, M E]] |
| - | [[Category: Joachimiak, A | + | [[Category: Freeman, L]] |
| - | [[Category: Kim, Y | + | [[Category: Joachimiak, A]] |
| - | [[Category: | + | [[Category: Kim, Y]] |
| - | [[Category: Rakowski, E | + | [[Category: Structural genomic]] |
| + | [[Category: Rakowski, E]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell inner membrane]] | [[Category: Cell inner membrane]] | ||
| Line 23: | Line 41: | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Midwest center for structural genomic]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
Current revision
Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.
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Categories: Ecol6 | Histidine kinase | Large Structures | Cuff, M E | Freeman, L | Joachimiak, A | Kim, Y | Structural genomic | Rakowski, E | Atp-binding | Cell inner membrane | Cell membrane | Histidine phosphotransfer domain | Htp | Kinase | Mcsg | Membrane | Nucleotide-binding | Phosphoprotein | PSI, Protein structure initiative | Transcription | Transcription regulation | Transferase | Transmembrane | Two-component regulatory system
