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Transthyretin 3D structures
From Proteopedia
(Difference between revisions)
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**[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | **[[3u2j]], [[4pvm]] – hTTR - neutron<br /> | ||
**[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant)<br /> | **[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant)<br /> | ||
| + | **[[7ob4]] - hTTR – Cryo EM<br /> | ||
**[[6sdz]] - hTTR (amyloidogenic mutant) – Cryo EM<br /> | **[[6sdz]] - hTTR (amyloidogenic mutant) – Cryo EM<br /> | ||
**[[1ttr]] – hTTR (cardiomyapatic mutant) | **[[1ttr]] – hTTR (cardiomyapatic mutant) | ||
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**[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | **[[4abq]], [[4abv]], [[4abw]], [[4ac2]], [[4ac4]], [[4act]], [[4ank]], [[4abu]] – hTTR + ligand<br /> | ||
**[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | **[[4des]], [[4det]], [[4der]], [[4dew]], [[4deu]] – hTTR + flavonoid<br /> | ||
| + | **[[7erh]] – hTTR + inhibitor<br /> | ||
**[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]], [[5e23]], [[5e4a]], [[5e4o]], [[5ezp]], [[5ayt]], [[4ydm]], [[4ydn]], [[4tq8]], [[4tqh]], [[4tqi]], [[4tqp]], [[5jim]], [[5jid]], [[6gr7]], [[6grp]], [[6ep1]], [[5u4g]], [[6tjn]], [[6ti9]] – hTTR + inhibitor<br /> | **[[1u21]], [[3cfn]], [[3cfq]], [[3cft]], [[3hj0]], [[3nee]], [[3neo]], [[3p3r]], [[3p3s]], [[3p3t]], [[3p3u]], [[4ky2]], [[4mas]], [[5e23]], [[5e4a]], [[5e4o]], [[5ezp]], [[5ayt]], [[4ydm]], [[4ydn]], [[4tq8]], [[4tqh]], [[4tqi]], [[4tqp]], [[5jim]], [[5jid]], [[6gr7]], [[6grp]], [[6ep1]], [[5u4g]], [[6tjn]], [[6ti9]] – hTTR + inhibitor<br /> | ||
| - | **[[3nes]], [[3nex]] – hTTR (mutant) + inhibitor<br /> | + | **[[3nes]], [[3nex]], [[7dt3]], [[7dt5]], [[7dt6]], [[7dt8]], [[7ejq]], [[7ejr]], [[7erj], [[7eri]] – hTTR (mutant) + inhibitor<br /> |
**[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]], [[5hjg]], [[5l4j]] – hTTR + phenol derivative<br /> | **[[1e3f]], [[1e4h]], [[1e5a]], [[2b15]], [[5hjg]], [[5l4j]] – hTTR + phenol derivative<br /> | ||
**[[4l1s]] - hTTR + benzamide derivative<br /> | **[[4l1s]] - hTTR + benzamide derivative<br /> | ||
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**[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]], [[5l4i]], [[6e70]], [[6d0w]] – hTTR + NSAID drug<br /> | **[[1y1d]], [[2b77]], [[2b9a]], [[3d2t]], [[3fc8]], [[3fcb]], [[2f7i]], [[4ikl]], [[4ikk]], [[4ikl]], [[4iki]], [[4ik7]], [[4ik6]], [[4iiz]], [[4ikj]], [[5l4i]], [[6e70]], [[6d0w]] – hTTR + NSAID drug<br /> | ||
| - | **[[4i89]], [[6e78]], [[6e73]] - hTTR (mutant) + NSAID drug<br /> | + | **[[4i89]], [[6e78]], [[6e73]], [[7erk]] - hTTR (mutant) + NSAID drug<br /> |
**[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br /> | **[[4i87]], [[4i85]] - hTTR (mutant) + fibrillogenesis inhibitor <br /> | ||
**[[3b56]] – hTTR + salicylic acid derivative<br /> | **[[3b56]] – hTTR + salicylic acid derivative<br /> | ||
Revision as of 08:57, 16 May 2022
3D structures of transthyretin
Updated on 16-May-2022 - For a general description of the protein see Transthyretin {{#tree:id=OrganizedByTopic|openlevels=0|
- Transthyretin
- 2pab, 1tta, 1ttb, 1etb, 1bmz, 1f41, 1dvq, 1fh2, 1qwh, 2h4e, 2qgb, 3cbr, 3d7p, 3cfm, 3i9p, 3a4d, 3a4e, 3a4f, 3u2i, 3w3b, 4mrb, 4pvl, 4pvn, 5k1j, 5k1n, 5cn3, 5cnh, 5dwp, 4tlt, 5lll, 5n7c, 5n62, 5n5q, 3ssg, 1zcr, 1zd6 – hTTR – human
- 3u2j, 4pvm – hTTR - neutron
- 1eta, 1ttc, 1tsh, 2trh, 2try, 1bzd, 1bze, 1fhn, 1g1o, 1x7s, 2qel, 3dgd, 3did, 3kgs, 3tfb – hTTR (amyloidogenic mutant)
- 7ob4 - hTTR – Cryo EM
- 6sdz - hTTR (amyloidogenic mutant) – Cryo EM
- 1ttr – hTTR (cardiomyapatic mutant)
- 2pab, 1tta, 1ttb, 1etb, 1bmz, 1f41, 1dvq, 1fh2, 1qwh, 2h4e, 2qgb, 3cbr, 3d7p, 3cfm, 3i9p, 3a4d, 3a4e, 3a4f, 3u2i, 3w3b, 4mrb, 4pvl, 4pvn, 5k1j, 5k1n, 5cn3, 5cnh, 5dwp, 4tlt, 5lll, 5n7c, 5n62, 5n5q, 3ssg, 1zcr, 1zd6 – hTTR – human
- 1bz8, 5ttr, 1f86, 1gko, 1iii, 1iik, 1ijn, 1sok, 1soq, 1x7t, 2g3x, 2g3z, 2g4e, 2g4g, 2noy, 3bt0, 3cxf, 3djr, 3djs, 3djt, 3djz, 3dk0, 3dk2, 3do4, 3gps, 3grb, 3grg, 3i9a, 3i9i, 4mrc, 4pwe, 5dej, 5clx, 5clx, 5clz, 5cm1, 4tlu, 4tnf, 4tng, 4tkw, 4tl4, 4tl5, 4tlk, 4tls, 4tm9, 4tne, 5llv, 5h0z, 5h0y, 5h0x, 5h0w, 5h0v, 5fw8, 5fw7, 5fw6, 5fo2, 5cly, 6fzl, 6fxu, 6fwd, 6e71, 6e75, 6e76, 5oq0, 5nfw, 5nfe, 6kgb – hTTR (mutant)
- 2nbp, 2nbo – hTTR (mutant) – NMR
- 2qpf – TTR - mouse
- 1bz8, 5ttr, 1f86, 1gko, 1iii, 1iik, 1ijn, 1sok, 1soq, 1x7t, 2g3x, 2g3z, 2g4e, 2g4g, 2noy, 3bt0, 3cxf, 3djr, 3djs, 3djt, 3djz, 3dk0, 3dk2, 3do4, 3gps, 3grb, 3grg, 3i9a, 3i9i, 4mrc, 4pwe, 5dej, 5clx, 5clx, 5clz, 5cm1, 4tlu, 4tnf, 4tng, 4tkw, 4tl4, 4tl5, 4tlk, 4tls, 4tm9, 4tne, 5llv, 5h0z, 5h0y, 5h0x, 5h0w, 5h0v, 5fw8, 5fw7, 5fw6, 5fo2, 5cly, 6fzl, 6fxu, 6fwd, 6e71, 6e75, 6e76, 5oq0, 5nfw, 5nfe, 6kgb – hTTR (mutant)
- Transthyretin binary complexes
- 1dvs, 1dvt, 1dvu, 1dvx, 1dvy, 1dvz, 1tt6, 1tz8, 2f8i, 2fbr, 2flm, 2g5u, 2g9k, 2gab, 2qgc, 2qgd, 2qge, 3cn0, 3cn1, 3cn2, 3cn3, 3cn4, 3esn, 3eso, 3esp, 3glz, 3gs0, 3gs4, 3gs7, 3imr, 3ims, 3imt, 3imu, 3imv, 3imw, 3ipb, 3ipe, 3m10, 2fbr, 2flm, 3m1o, 3tct, 4fi7, 4fi8, 4fi6, 5tzl, 6e6z – hTTR + amyloid disease inhibitor
- 4his, 4hiq, 6imx, 6imy, 6e72, 6e74, 6e77 - hTTR (mutant) + amyloid disease inhibitor
- 6fft - hTTR (mutant) + amyloid disease inhibitor - Neutron
- 4abq, 4abv, 4abw, 4ac2, 4ac4, 4act, 4ank, 4abu – hTTR + ligand
- 4des, 4det, 4der, 4dew, 4deu – hTTR + flavonoid
- 7erh – hTTR + inhibitor
- 1u21, 3cfn, 3cfq, 3cft, 3hj0, 3nee, 3neo, 3p3r, 3p3s, 3p3t, 3p3u, 4ky2, 4mas, 5e23, 5e4a, 5e4o, 5ezp, 5ayt, 4ydm, 4ydn, 4tq8, 4tqh, 4tqi, 4tqp, 5jim, 5jid, 6gr7, 6grp, 6ep1, 5u4g, 6tjn, 6ti9 – hTTR + inhibitor
- 3nes, 3nex, 7dt3, 7dt5, 7dt6, 7dt8, 7ejq, 7ejr, [[7erj], 7eri – hTTR (mutant) + inhibitor
- 1e3f, 1e4h, 1e5a, 2b15, 5hjg, 5l4j – hTTR + phenol derivative
- 4l1s - hTTR + benzamide derivative
- 4l1t - hTTR + benzoate derivative
- 5jiq - hTTR + benzophenone derivative
- 5l4m, 6grp - hTTR + pyridine derivative
- 4n85, 4n86 - hTTR + glabridin
- 4n87 - hTTR (mutant) + glabridin
- 2b14, 2b16 – hTTR (mutant) + phenol derivative
- 6r66, 6r67, 6r68 - hTTR + flurbiprofen analog
- 6r6i - hTTR (mutant) + flurbiprofen analog
- 3kgt, 3kgu, 5akv – hTTR (mutant) + genistein derivative
- 1dvs, 1dvt, 1dvu, 1dvx, 1dvy, 1dvz, 1tt6, 1tz8, 2f8i, 2fbr, 2flm, 2g5u, 2g9k, 2gab, 2qgc, 2qgd, 2qge, 3cn0, 3cn1, 3cn2, 3cn3, 3cn4, 3esn, 3eso, 3esp, 3glz, 3gs0, 3gs4, 3gs7, 3imr, 3ims, 3imt, 3imu, 3imv, 3imw, 3ipb, 3ipe, 3m10, 2fbr, 2flm, 3m1o, 3tct, 4fi7, 4fi8, 4fi6, 5tzl, 6e6z – hTTR + amyloid disease inhibitor
- 3ng5 – hTTR (mutant) + epigallocatechin gallate
- 1tyr – hTTR + retinoic acid
- 1z7j - hTTR + tetraiodotyroacetic acid
- 1y1d, 2b77, 2b9a, 3d2t, 3fc8, 3fcb, 2f7i, 4ikl, 4ikk, 4ikl, 4iki, 4ik7, 4ik6, 4iiz, 4ikj, 5l4i, 6e70, 6d0w – hTTR + NSAID drug
- 4i89, 6e78, 6e73, 7erk - hTTR (mutant) + NSAID drug
- 4i87, 4i85 - hTTR (mutant) + fibrillogenesis inhibitor
- 3b56 – hTTR + salicylic acid derivative
- 4hjs, 4hjt, 4hju – hTTR + covalent kinetic stabilizer
- 4pmf - hTTR + curcumin
- 4qxv, 5en3, 5ihh - hTTR + luteolin
- 4qya - hTTR (mutant) + luteolin
- 4pwf - hTTR (mutant) + ferulic esterase
- 4pwg, 4pwh, 4qrf - hTTR (mutant) + caffeic esterase
- 4pwi - hTTR (mutant) + rosamariic acid
- 4pwj, 4pwk - hTTR (mutant) + propolis
- 4d7b, 6suh, 6sug - hTTR + tolcapone analog
- 5a6i, 6xtk, 6txw, 6txv - hTTR (mutant) + tolcapone
- 5aks, 5akt, 5al0- hTTR + resveratrol
- 5al8 - hTTR + daidzein glucuronide
- 4y9b, 4y9c, 4y9e, 4y9f, 4y9g - hTTR (mutant) + mangostin
- 4wnj - hTTR + quercetin
- 5l4f - hTTR + cresol derivative
- 4wns, 5u48, 5u49, 5u4a, 5u4b, 5u4c, 5u4d, 5u4e, 5u4f 5u4g - hTTR + stilbene derivative
- 4wo0 - hTTR + apigenin
- 5boj - hTTR + gemfibrozil
- 7acu - hTTR + benzbromarone
- 1kgi – rTTR + tetraiodotyroacetic acid
- 1kgj – rTTR + dibromoflavone
- 6gnm - sbTTR + benzophenone derivative
- 6gno, 6gnw - sbTTR + phenol derivative
- 6gnp, 6gnr - sbTTR + pyridine derivative
- 6gon, 6goo - sbTTR + perfluorooctanoate
- 6gnw, 6gno, 6gnp, 6gnr, 6gnm, 6gon, 6goo - sbTTR + inhibitor
- 1y1d, 2b77, 2b9a, 3d2t, 3fc8, 3fcb, 2f7i, 4ikl, 4ikk, 4ikl, 4iki, 4ik7, 4ik6, 4iiz, 4ikj, 5l4i, 6e70, 6d0w – hTTR + NSAID drug
- Transthyretin ternary complexes
- Transthyretin complexes with retinol-binding protein
- 2wqa – hTTR + RBP + oleic acid
- 3bsz – hTTR + RBP + antibody
- Transthyretin complexes with thyroxine
- 3ozk – hTTR (mutant) + T4
- 1ie4 – rTTR + T4
- 1sn0 – sbTTR + T4
- 1sn5 – sbTTR + T4 derivative
- Transthyretin peptide amyloid forming
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