3pjs
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Mechanism of Activation Gating in the Full-Length KcsA K+ Channel== | ==Mechanism of Activation Gating in the Full-Length KcsA K+ Channel== | ||
| - | <StructureSection load='3pjs' size='340' side='right' caption='[[3pjs]], [[Resolution|resolution]] 3.80Å' scene=''> | + | <StructureSection load='3pjs' size='340' side='right'caption='[[3pjs]], [[Resolution|resolution]] 3.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pjs]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3pjs]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_lividans"_krasil'nikov_et_al._1965 "actinomyces lividans" krasil'nikov et al. 1965] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJS FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kcsA, skc1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kcsA, skc1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1916 "Actinomyces lividans" Krasil'nikov et al. 1965])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjs OCA], [https://pdbe.org/3pjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pjs RCSB], [https://www.ebi.ac.uk/pdbsum/3pjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pjs ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 20: | ||
==See Also== | ==See Also== | ||
| - | *[[Potassium | + | *[[Antibody 3D structures|Antibody 3D structures]] |
| - | *[[3D structures of antibody|3D structures of antibody]] | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] |
| + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 27: | Line 28: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Actinomyces lividans krasil'nikov et al. 1965]] | [[Category: Actinomyces lividans krasil'nikov et al. 1965]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Cuello, L G]] | [[Category: Cuello, L G]] | ||
Revision as of 08:42, 25 May 2022
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
| |||||||||||
