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3qq5

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[[Image:3qq5.png|left|200px]]
 
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==Crystal structure of the [FeFe]-hydrogenase maturation protein HydF==
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The line below this paragraph, containing "STRUCTURE_3qq5", creates the "Structure Box" on the page.
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<StructureSection load='3qq5' size='340' side='right'caption='[[3qq5]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thenn Thenn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QQ5 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1feh|1feh]], [[3ciw|3ciw]], [[3lx4|3lx4]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTN_0227 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=309803 THENN])</td></tr>
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{{STRUCTURE_3qq5| PDB=3qq5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qq5 OCA], [https://pdbe.org/3qq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qq5 RCSB], [https://www.ebi.ac.uk/pdbsum/3qq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qq5 ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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[FeFe]-hydrogenases catalyze the reversible pro-duction of H2 in some bacteria and unicellular eu-karyotes. These enzymes require ancillary proteins to assemble the unique active site H-cluster, a com-plex structure composed of a 2Fe center bridged to a [4Fe-4S] cubane. The first crystal structure of a key factor in the maturation process, HydF, has been determined at 3A resolution. The protein monomer present in the asymmetric unit of the crystal comprises three domains: a GTP-binding domain, a dimerization domain and a metal-cluster binding domain, all characterized by similar fold-ing motifs. Two monomers dimerize, giving rise to a stable dimer, held together mainly by the for-mation of a continuous beta-sheet comprising eight beta-strands from two monomers. Moreover, in the structure presented two dimers aggregate to form a supramolecular organization that represents an in-activated form of the HydF maturase. The crystal structure of the latter furnishes several clues about the events necessary for cluster genera-tion/transfer, and provides an excellent model to begin elucidating the structure/function of HydF in [FeFe]-hydrogenase maturation.
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===Crystal structure of the [FeFe]-hydrogenase maturation protein HydF===
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Crystal structure of HydF scaffold protein provides insights into [FeFe]-hydrogenase maturation.,Cendron L, Berto P, D'Adamo S, Vallese F, Govoni C, Posewitz MC, Giacometti GM, Costantini P, Zanotti G J Biol Chem. 2011 Nov 4. PMID:22057316<ref>PMID:22057316</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_22057316}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3qq5" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 22057316 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22057316}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3qq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_neapolitana Thermotoga neapolitana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQ5 OCA].
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[[Category: Thenn]]
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[[Category: Adamo, S D]]
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==Reference==
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[[Category: Berto, P]]
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<ref group="xtra">PMID:022057316</ref><references group="xtra"/>
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[[Category: Cendron, L]]
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[[Category: Thermotoga neapolitana]]
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[[Category: Costantini, P]]
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[[Category: Adamo, S D.]]
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[[Category: Giacometti, G M]]
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[[Category: Berto, P.]]
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[[Category: Govoni, C]]
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[[Category: Cendron, L.]]
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[[Category: Posewitz, M C]]
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[[Category: Costantini, P.]]
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[[Category: Vallese, F]]
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[[Category: Giacometti, G M.]]
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[[Category: Zanotti, G]]
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[[Category: Govoni, C.]]
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[[Category: Posewitz, M C.]]
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[[Category: Vallese, F.]]
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[[Category: Zanotti, G.]]
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[[Category: Gtp-binding domain]]
[[Category: Gtp-binding domain]]
[[Category: H-cluster]]
[[Category: H-cluster]]

Current revision

Crystal structure of the [FeFe]-hydrogenase maturation protein HydF

PDB ID 3qq5

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