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3qsc
From Proteopedia
(Difference between revisions)
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==The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a copper complex)== | ==The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a copper complex)== | ||
| - | <StructureSection load='3qsc' size='340' side='right' caption='[[3qsc]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='3qsc' size='340' side='right'caption='[[3qsc]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qsc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSC OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[3qsc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSC FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUF:[2,2-{(4,5-DIFLUOROBENZENE-1,2-DIYL)BIS[(NITRILO-KAPPAN)METHYLYLIDENE]}BIS{5-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOLATO-KAPPAO}(2-)]COPPER+(II)'>CUF</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CUF:[2,2-{(4,5-DIFLUOROBENZENE-1,2-DIYL)BIS[(NITRILO-KAPPAN)METHYLYLIDENE]}BIS{5-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOLATO-KAPPAO}(2-)]COPPER+(II)'>CUF</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ce5|3ce5]], [[3cco|3cco]], [[3cdm|3cdm]], [[1kf1|1kf1]], [[1k8p|1k8p]], [[2hri|2hri]], [[3qsf|3qsf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ce5|3ce5]], [[3cco|3cco]], [[3cdm|3cdm]], [[1kf1|1kf1]], [[1k8p|1k8p]], [[2hri|2hri]], [[3qsf|3qsf]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsc OCA], [https://pdbe.org/3qsc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsc RCSB], [https://www.ebi.ac.uk/pdbsum/3qsc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsc ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Campbell, N H]] | [[Category: Campbell, N H]] | ||
[[Category: Karim, N H.Abd]] | [[Category: Karim, N H.Abd]] | ||
Revision as of 06:22, 8 June 2022
The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a copper complex)
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Categories: Large Structures | Campbell, N H | Karim, N H.Abd | Neidle, S | Parkinson, G N | Vilar, R | Copper complex | Dna | Drug | Metal complex | Parallel | Quadruplex | Telomere
