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| - | ==Crystal structure of PGRP-S complexed with chorismate at 2.15 A resolution==
| + | #REDIRECT [[7xu8]] This PDB entry is obsolete and replaced by 7xu8 |
| - | <StructureSection load='3uml' size='340' side='right' caption='[[3uml]], [[Resolution|resolution]] 2.15Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3uml]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UML FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ISJ:(3R,4R)-3-[(1-CARBOXYETHENYL)OXY]-4-HYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC+ACID'>ISJ</scene></td></tr>
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| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c2x|3c2x]]</td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uml RCSB], [http://www.ebi.ac.uk/pdbsum/3uml PDBsum]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Camelus dromedarius]]
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| - | [[Category: Bhushan, A]]
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| - | [[Category: Kaur, P]]
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| - | [[Category: Sharma, P]]
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| - | [[Category: Sharma, S]]
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| - | [[Category: Singh, T P]]
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| - | [[Category: Sinha, M]]
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| - | [[Category: Yamini, S]]
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| - | [[Category: Antibiotic]]
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| - | [[Category: Antimicrobial]]
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| - | [[Category: Immune response]]
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| - | [[Category: Immune system]]
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| - | [[Category: Peptidoglycan binding]]
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| - | [[Category: Pgrp-]]
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| - | [[Category: Secreted]]
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Current revision
- REDIRECT 7xu8 This PDB entry is obsolete and replaced by 7xu8
