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3qwh
From Proteopedia
(Difference between revisions)
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==Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol== | ==Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol== | ||
| - | <StructureSection load='3qwh' size='340' side='right' caption='[[3qwh]], [[Resolution|resolution]] 2.62Å' scene=''> | + | <StructureSection load='3qwh' size='340' side='right'caption='[[3qwh]], [[Resolution|resolution]] 2.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qwh]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qwh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_730.96 Cbs 730.96]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWH FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KMP:3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE'>KMP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KMP:3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE'>KMP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3is3|3is3]], [[3itd|3itd]], [[3qwf|3qwf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3is3|3is3]], [[3itd|3itd]], [[3qwf|3qwf]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">17HSDcl ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">17HSDcl ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5503 CBS 730.96])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwh OCA], [https://pdbe.org/3qwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwh RCSB], [https://www.ebi.ac.uk/pdbsum/3qwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwh ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 3qwh" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3qwh" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: 17-beta-estradiol 17-dehydrogenase]] | [[Category: 17-beta-estradiol 17-dehydrogenase]] | ||
[[Category: Cbs 730 96]] | [[Category: Cbs 730 96]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Brunskole, M]] | [[Category: Brunskole, M]] | ||
[[Category: Cassetta, A]] | [[Category: Cassetta, A]] | ||
Revision as of 05:39, 15 June 2022
Crystal structure of the 17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus in complex with NADPH and kaempferol
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Categories: 17-beta-estradiol 17-dehydrogenase | Cbs 730 96 | Large Structures | Brunskole, M | Cassetta, A | Krastanova, I | Kristan, K | Lamba, D | Rizner, T L | Stojan, J | 17beta-hydroxysteroid dehydrogenase | Cytosol | Flavonoid | Oxidoreductase-oxidoreductase inhibitor complex | Phytoestrogen | Rossmann fold | Short chain dehydrogenase/reductase
