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3qz1
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)== | ==Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)== | ||
| - | <StructureSection load='3qz1' size='340' side='right' caption='[[3qz1]], [[Resolution|resolution]] 3.00Å' scene=''> | + | <StructureSection load='3qz1' size='340' side='right'caption='[[3qz1]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qz1]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qz1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QZ1 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3QZ:(9BETA)-17-HYDROXYPREGN-4-ENE-3,20-DIONE'>3QZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3QZ:(9BETA)-17-HYDROXYPREGN-4-ENE-3,20-DIONE'>3QZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP21, CYP21A1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP21, CYP21A1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Steroid_21-monooxygenase Steroid 21-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.10 1.14.99.10] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qz1 OCA], [https://pdbe.org/3qz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qz1 RCSB], [https://www.ebi.ac.uk/pdbsum/3qz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qz1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CP21A_BOVIN CP21A_BOVIN]] Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bovin]] | [[Category: Bovin]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Steroid 21-monooxygenase]] | [[Category: Steroid 21-monooxygenase]] | ||
[[Category: Waterman, M R]] | [[Category: Waterman, M R]] | ||
Revision as of 05:42, 15 June 2022
Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)
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