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3r7c
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of a hexahestidine-tagged form of augmenter of liver regeneration reveals a novel Cd(2)Cl(4)O(6) cluster that aids in crystal packing== |
| + | <StructureSection load='3r7c' size='340' side='right'caption='[[3r7c]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3r7c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R7C FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1oqc|1oqc]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Alr, Gfer, Gfer (ALR) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thiol_oxidase Thiol oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.3.2 1.8.3.2] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r7c OCA], [https://pdbe.org/3r7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r7c RCSB], [https://www.ebi.ac.uk/pdbsum/3r7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r7c ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/ALR_RAT ALR_RAT]] FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs. May have a function in liver regeneration and spermatogenesis.<ref>PMID:8058770</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Sulfhydryl oxidase 3D structures|Sulfhydryl oxidase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Buffalo rat]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thiol oxidase]] | ||
| + | [[Category: Florence, Q J]] | ||
| + | [[Category: II, J T.Swindell]] | ||
| + | [[Category: Rose, J P]] | ||
| + | [[Category: Wang, B C]] | ||
| + | [[Category: Wu, C K]] | ||
| + | [[Category: All-helical fad binding motif]] | ||
| + | [[Category: Fad binding]] | ||
| + | [[Category: Fad-linked sulfhydryl oxidase]] | ||
| + | [[Category: Four-helical up-and-down bundle]] | ||
| + | [[Category: Liver regeneration]] | ||
| + | [[Category: Mitochondrial intermembrane space]] | ||
| + | [[Category: Oxidoreductase]] | ||
Current revision
The structure of a hexahestidine-tagged form of augmenter of liver regeneration reveals a novel Cd(2)Cl(4)O(6) cluster that aids in crystal packing
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Categories: Buffalo rat | Large Structures | Thiol oxidase | Florence, Q J | II, J T.Swindell | Rose, J P | Wang, B C | Wu, C K | All-helical fad binding motif | Fad binding | Fad-linked sulfhydryl oxidase | Four-helical up-and-down bundle | Liver regeneration | Mitochondrial intermembrane space | Oxidoreductase
