This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3re3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:59, 15 June 2022) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3re3.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase from Francisella tularensis==
-
The line below this paragraph, containing "STRUCTURE_3re3", creates the "Structure Box" on the page.
+
<StructureSection load='3re3' size='340' side='right'caption='[[3re3]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3re3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RE3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
-
-->
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_3re3| PDB=3re3 | SCENE= }}
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTT_1128, ispF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3re3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3re3 OCA], [https://pdbe.org/3re3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3re3 RCSB], [https://www.ebi.ac.uk/pdbsum/3re3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3re3 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/ISPF_FRATT ISPF_FRATT]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
-
===Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase from Francisella tularensis===
+
==See Also==
-
 
+
*[[MECDP synthase 3D structures|MECDP synthase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[3re3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RE3 OCA].
+
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
-
[[Category: Francisella tularensis subsp. tularensis]]
+
[[Category: Fratt]]
-
[[Category: Anderson, W F.]]
+
[[Category: Large Structures]]
-
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+
[[Category: Anderson, W F]]
-
[[Category: Joachimiak, A.]]
+
[[Category: Structural genomic]]
-
[[Category: Kim, Y.]]
+
[[Category: Joachimiak, A]]
-
[[Category: Kwon, K.]]
+
[[Category: Kim, Y]]
-
[[Category: Makowska-Grzyska, M.]]
+
[[Category: Kwon, K]]
 +
[[Category: Makowska-Grzyska, M]]
 +
[[Category: Alpha-beta half sandwich]]
 +
[[Category: Csgid]]
 +
[[Category: Cytosol]]
 +
[[Category: Lyase]]

Current revision

Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase from Francisella tularensis

PDB ID 3re3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools