3D structures of ubiquitin conjugating enzyme

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(New page: == 3D Structures of ubiquitin conjugating enzyme == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Ubiquitin...)
Line 28: Line 28:
**[[1ayz]] – yUbc <BR />
**[[1ayz]] – yUbc <BR />
**[[4r62]] – yUbc + ubiquitin carboxyl extension protein 80 <BR />
**[[4r62]] – yUbc + ubiquitin carboxyl extension protein 80 <BR />
 +
**[[7mex]], [[7mey]] – yUbc + ubiquitin + degron + E3 – Cryo EM <BR />
**[[5aie]] – yUbc + NOT4 <BR />
**[[5aie]] – yUbc + NOT4 <BR />
**[[1z2u]] – CeUbc <BR />
**[[1z2u]] – CeUbc <BR />
Line 48: Line 49:
**[[2awf]], [[2cyx]] – hUbc<BR />
**[[2awf]], [[2cyx]] – hUbc<BR />
 +
**[[6xxu]] – hUbc - NMR <BR />
 +
**[[7v8f]] – hUbc + E3 <BR />
 +
**[[7oik]] – hUbc + E3 – Cryo EM<BR />
**[[6xxu]] – hUbc - NMR<BR />
**[[6xxu]] – hUbc - NMR<BR />
**[[1c4z]] – hUbc + E3 HECT domain <BR />
**[[1c4z]] – hUbc + E3 HECT domain <BR />
Line 60: Line 64:
**[[5tte]], [[5udh]] – hUbc (mutant) + ubiquitin + ARIH1<BR />
**[[5tte]], [[5udh]] – hUbc (mutant) + ubiquitin + ARIH1<BR />
**[[5hpt]] – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein<BR />
**[[5hpt]] – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein<BR />
 +
**[[7b5l]], [[7b5n]] – hUbc + hPolyUBB-C + Cul1 + Nedd8 + RBX1 + ARITH1 – Cryo EM<br />
**[[2ucz]] – yUbc <BR />
**[[2ucz]] – yUbc <BR />
Line 119: Line 124:
**[[4whv]], [[6s53]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase<BR />
**[[4whv]], [[6s53]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase<BR />
**[[5ait]], [[5aiu]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4<BR />
**[[5ait]], [[5aiu]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4<BR />
 +
**[[7bbf]], [[7myh]] – hUbc + polyubiquitin-C <BR />
 +
**[[6ulh]], [[6ump]], [[6ums]], [[7bxg] – hUbc + polyubiquitin-C + MavC<BR />
 +
**[[7bbd]] – hUbc + polyubiquitin-C + E3<BR />
**[[4orh]] – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8<BR />
**[[4orh]] – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8<BR />
**[[4ip3]], [[3w31]] – hUbc + Orf169b <BR />
**[[4ip3]], [[3w31]] – hUbc + Orf169b <BR />
**[[2oxq]] – Ubc + CHIP U-box - zebrafish<BR />
**[[2oxq]] – Ubc + CHIP U-box - zebrafish<BR />
 +
**[[6zhs]], [[6zht]] – yUbc + E1<BR />
**[[5ojw]] – yUbc + Mms2 <BR />
**[[5ojw]] – yUbc + Mms2 <BR />
**[[6jky]] – yUbc + ubiquitin + MvcA <BR />
**[[6jky]] – yUbc + ubiquitin + MvcA <BR />
Line 154: Line 163:
**[[2esk]], [[2clw]], [[3l1y]], [[3tgd]] – hUbc D2 <BR />
**[[2esk]], [[2clw]], [[3l1y]], [[3tgd]] – hUbc D2 <BR />
-
**[[2eso]], [[2esp]], [[2esq]] – hUbc D2 (mutant)<BR />
+
**[[2eso]], [[2esp]], [[2esq]] – hUbc, [[7bol]]D2 (mutant)<BR />
**[[1w4u]] – hUbc D2 - NMR<BR />
**[[1w4u]] – hUbc D2 - NMR<BR />
**[[4ddg]], [[4ddi]], [[5ulf]] – hUbc D2 + ubiquitin<BR />
**[[4ddg]], [[4ddi]], [[5ulf]] – hUbc D2 + ubiquitin<BR />
Line 169: Line 178:
**[[5d0k]], [[5d0m]] – hUbc D2 + UBB + RING finger protein 165<BR />
**[[5d0k]], [[5d0m]] – hUbc D2 + UBB + RING finger protein 165<BR />
**[[4ldt]] – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde<BR />
**[[4ldt]] – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde<BR />
-
**[[4wz3]] – hUbc D2 + E3 ubiquitin-protein ligase LubX<BR />
+
**[[4wz3]], [[6w7z]] – hUbc D2 + E3 ubiquitin-protein ligase LubX<BR />
 +
**[[6w9d]], [[7ahz]], [[7ai0]], [[7ai1]], [[7r71]] – hUbc D2 + E3 ubiquitin-protein ligase + Ub<BR />
**[[5v2w]] – hUbc D2 (mutant) + ubiquitin + TRIM23<BR />
**[[5v2w]] – hUbc D2 (mutant) + ubiquitin + TRIM23<BR />
**[[1ur6]] – hUbc D2 + Cnot4 - NMR<BR />
**[[1ur6]] – hUbc D2 + Cnot4 - NMR<BR />
Line 188: Line 198:
**[[6cp0]] – hUbc D3 + SdcA<BR />
**[[6cp0]] – hUbc D3 + SdcA<BR />
**[[6t7f]] – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2<BR />
**[[6t7f]] – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2<BR />
 +
**[[7jzv]], [[7lyb]] – hUbc D3 in nucleosome complex – Cryo EM <BR />
*Ubiquitin conjugating enzyme E1
*Ubiquitin conjugating enzyme E1
Line 209: Line 220:
**[[2lxp]] – hUbc + AMFR peptide - NMR<BR />
**[[2lxp]] – hUbc + AMFR peptide - NMR<BR />
**[[3h8k]], [[4lad]] – hUbc + AMFR peptide <BR />
**[[3h8k]], [[4lad]] – hUbc + AMFR peptide <BR />
 +
**[[7lew]] – hUbc + AUP1 peptide <BR />
*Ubiquitin conjugating enzyme H
*Ubiquitin conjugating enzyme H
Line 220: Line 232:
*Ubiquitin conjugating enzyme K
*Ubiquitin conjugating enzyme K
-
**[[5dfl]], [[6if1]] – hUbc + ubiquitin <BR />
+
**[[5dfl]], [[6if1]], [[7myf]] – hUbc + ubiquitin <BR />
-
[[6jb6]], [[6jb7]] – hUbc (mutant) + ubiquitin <BR />
+
**[[6jb6]], [[6jb7]] – hUbc (mutant) + ubiquitin <BR />
 +
**[[7ojx]] – hUbc + polyubiquitin-B + E3<BR />
*Ubiquitin conjugating enzyme Q1
*Ubiquitin conjugating enzyme Q1
Line 229: Line 242:
*Ubiquitin conjugating enzyme R1
*Ubiquitin conjugating enzyme R1
-
**[[3rz3]] – hUbc + inhibitor <BR />
+
**[[3rz3]], [[7m2k]] – hUbc + inhibitor <BR />
**[[4mdk]] – hUbc + ubiquitin + inhibitor <BR />
**[[4mdk]] – hUbc + ubiquitin + inhibitor <BR />
Line 239: Line 252:
**[[1zdn]] – hUbc <BR />
**[[1zdn]] – hUbc <BR />
 +
**[[7ahf]] – hUbc (mutant)<BR />
**[[6qhk]], [[6s98]] – hUbc catalytic domain<BR />
**[[6qhk]], [[6s98]] – hUbc catalytic domain<BR />
**[[6qh3]], [[6s96]] – hUbc catalytic domain (mutant)<BR />
**[[6qh3]], [[6s96]] – hUbc catalytic domain (mutant)<BR />
Line 270: Line 284:
**[[3f92]] – hHIP-2/azorectase (mutant) <BR />
**[[3f92]] – hHIP-2/azorectase (mutant) <BR />
**[[3k9o]], [[3k9p]] – hHIP-2 + ubiquitin <BR />
**[[3k9o]], [[3k9p]] – hHIP-2 + ubiquitin <BR />
 +
 +
*Ubc E2-34KDa
 +
 +
**[[6zhu]], [[7k5j]] – yUbc + E1 + ATP <BR />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:35, 16 June 2022

3D Structures of ubiquitin conjugating enzyme

Updated on 16-June-2022 - For a general description of the protein see Ubiquitin conjugating enzyme {{#tree:id=OrganizedByTopic|openlevels=0|

  • Ubiquitin conjugating enzyme
    • 1jas – hUbc – human
    • 2aak – AtUbc – Arabidopsis thaliana
    • 2qcq, 1fzy – yUbc – yeast
    • 1fxt – yUbc + ubiquitin
    • 2e2c – Ubc – Spisula solidissima
    • 1q34 – CeUbc – Caenorhabidis elegans
    • 2fo3 – Ubc – Plasmodium vivax
    • 2h2y – PfUbc – Plasmodium falciparum
    • 6mj9, 5vor – Ubc – Naegleria fowleri
  • Ubiquitin conjugating enzyme 1
    • 2aak – AtUbc
    • 3we5 – Ubc – poplar mushroom
    • 1fzy – yUbc
    • 1tte – yUbc (mutant)
    • 1z3d – CeUbc
  • Ubiquitin conjugating enzyme 2
    • 1ayz – yUbc
    • 4r62 – yUbc + ubiquitin carboxyl extension protein 80
    • 7mex, 7mey – yUbc + ubiquitin + degron + E3 – Cryo EM
    • 5aie – yUbc + NOT4
    • 1z2u – CeUbc
  • Ubiquitin conjugating enzyme 3 or Ubc3 or Cdc34
  • Ubiquitin conjugating enzyme 4
    • 1qcq – yUbc
    • 5aie – yUbc + NOT4 RING domain
    • 4ii2 – fyUbc (mutant) + E1 + ATP – fission yeast
  • Ubiquitin conjugating enzyme 6
    • 4jjq – hUbc + ubiquitin carboxyl terminal hydrolase
  • Ubiquitin conjugating enzyme 7 or Ubc L3
    • 2awf, 2cyx – hUbc
    • 6xxu – hUbc - NMR
    • 7v8f – hUbc + E3
    • 7oik – hUbc + E3 – Cryo EM
    • 6xxu – hUbc - NMR
    • 1c4z – hUbc + E3 HECT domain
    • 1fbv – hUbc + E3 Cbl + ZAP-70 peptide
    • 4jqu – hUbc + U7BR
    • 3sqv – hUbc + secreted effector protein
    • 3sy2 – hUbc + E3 Sopa
    • 5udh – hUbc + ubiquitin + E3 ARIH1
    • 4q5e, 4q5h – hUbc (mutant) + ubiquitin + OspG
    • 6cp2 – hUbc (mutant) + UBB + SidC
    • 6djw, 6djx, 6n13 – hUbc (mutant) + ubiquitin + PARKIN
    • 5tte, 5udh – hUbc (mutant) + ubiquitin + ARIH1
    • 5hpt – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein
    • 7b5l, 7b5n – hUbc + hPolyUBB-C + Cul1 + Nedd8 + RBX1 + ARITH1 – Cryo EM
    • 2ucz – yUbc
  • Ubiquitin conjugating enzyme 8
    • 1y6l, 1wzw, 1wzv – hUbc
    • 2kjh – hUbc + ubiquitin
    • 4x57 – AtUbc + membrane-anchord ubiquitin-fold protein
  • Ubiquitin conjugating enzyme 10 or Ubc C
    • 1i7k – hUbc (mutant)
    • 4yii – hUbc + anaphase-promoting complex subunit 2
  • Ubiquitin conjugating enzyme 12 (NEDD8 conjugating enzyme; Ubc F)
    • 2edi – hUbc 2 UQ-CON domain - NMR
    • 1y8x – hUbc + E1 NEDD8
    • 1tt5 – hUbc + E1 Uba3, APPBP1 subunits
    • 1y8x – hUbc + E1 NEDD8
    • 2nvu – hUbc + E1 NEDD8 + NEDD8
    • 3fn1 – hUbc + E1 NEDD8-activating enzyme
    • 3tdu – hUbc + cullin-1 + Dcn1-like protein
    • 4p5o – hUbc + cullin-1 + Dcn1-like protein + Rbx1 + NEDD8
    • 4gao – hUbc + Dcn1-like protein
    • 3tdi – hUbc + defective in cullin neddylation protein
    • 3o2u – yUbc
  • Ubiquitin conjugating enzyme 13 or Ubc N
  • Ubiquitin conjugating enzyme 13 complexes
    • 2c2v – hUbc + CHIP + Uev1a
    • 3hct, 3hcu – hUbc + TNF receptor associated factor 6
    • 4dhi, 4dhz – hUbc + OTUB1 + ubiquitin + ubiquitin aldehyde
    • 4orh – hUbc/Mms2 + E3 Rnf8
    • 3von – hUbc/Mms2 + OTUB1
    • 1zgu – hMms2 + ubiquitin - NMR
    • 5eya – hUbc + ubiquitin + TRIM25 ring domain
    • 4tkp – hUbc + TRIM5 ring domain
    • 2gmi – hUbc/Mms2 (mutant) + ubiquitin
    • 4onl, 4onm, 4onn – hUbc + Mms2 (mutant)
    • 4nr3, 4nrg, 4nri – hUbc (mutant) + Mms2
    • 3von – hUbc + Otub1 + E2 variant
    • 6d6i – hUbc + ubiquitin + E2 variant
    • 4dhj – hUbc + ubiquitin + OTUB1
    • 5vnz, 5vo0 – hUbc + ubiquitin + TraF6
    • 6kl4, 7bxg, 6p5b, 6ulh, 6ump, 6ums – hUbc + ubiquitin + MavC
    • 6kfp, 6kg6 – hUbc + ubiquitin-RPS27a + MavC
    • 5ywr – hUbc + E3 ubiquitin-protein ligase ZANFR1
    • 4whv, 6s53 – hUbc + ubiquitin + E3 ubiquitin-protein ligase
    • 5ait, 5aiu – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4
    • 7bbf, 7myh – hUbc + polyubiquitin-C
    • 6ulh, 6ump, 6ums, [[7bxg] – hUbc + polyubiquitin-C + MavC
    • 7bbd – hUbc + polyubiquitin-C + E3
    • 4orh – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8
    • 4ip3, 3w31 – hUbc + Orf169b
    • 2oxq – Ubc + CHIP U-box - zebrafish
    • 6zhs, 6zht – yUbc + E1
    • 5ojw – yUbc + Mms2
    • 6jky – yUbc + ubiquitin + MvcA
    • 4dhi – CeUbc + OTUB1
  • Ubiquitin conjugating enzyme 16 or Ubc W
    • 2mt6 – hUbc - NMR
  • Ubiquitin conjugating enzyme A or Rad6
    • 6cyo – hUbc A
    • 6cyr – hUbc A (mutant)
  • Ubiquitin conjugating enzyme B
  • Ubiquitin conjugating enzyme D1
    • 2c4p – hUbc D1
    • 2yho – hUbc D1 + E3 Mylip
    • 5fer – hUbc D1 + ubiquitin carboxyl extension protein 80 + TRIM25 ring
    • 4qpl – hUbc D1 + E3 ubiquitin-protein ligase RNF146
    • 3ptf, 6d4p, 5tut – hUbc D1 + ubiquitin
    • 4ap4 – hUbc D1 + E3 ubiquitin-protein ligase RNF4 + ubiquitin
    • 3oj4 – hUbc D1 + tumor necrosis factor α-induced protein 3 + ubiquitin
  • Ubiquitin conjugating enzyme D2
    • 2esk, 2clw, 3l1y, 3tgd – hUbc D2
    • 2eso, 2esp, 2esq – hUbc, 7bolD2 (mutant)
    • 1w4u – hUbc D2 - NMR
    • 4ddg, 4ddi, 5ulf – hUbc D2 + ubiquitin
    • 5ulf, 3a33 – hUbc D2 (mutant) + ubiquitin
    • 4ldt – hUbc D2 + Otub1 + ubiquitin
    • 5d1k, 5d1l, 5d1m – hUbc D2 + E3 ubiquitin-protein ligase RNF25
    • 5edv – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF31
    • 4a49 – hUbc D2 + E3 ubiquitin-protein ligase CBL-B
    • 4v3k, 4v3l, 4a4b, 4a4c – hUbc D2 + ZAP peptide + E3 ubiquitin-protein ligase CBL-B
    • 3zni, 6w9d, 6w7z, 5ulh, 5vzw, 5zbu – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase
    • 6sqo, 6sqs, 6sqr – hUbc D2 + ubiquitin-RPS27a + E3 ubiquitin-protein ligase Mdm2
    • 5ulh, 5ulk – hUbc D2 (mutant) + ubiquitin + E3 ubiquitin-protein ligase RNF165
    • 5mnj – hUbc D2 (mutant) + UBB + Mdm2 + Mdm4
    • 5d0k, 5d0m – hUbc D2 + UBB + RING finger protein 165
    • 4ldt – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde
    • 4wz3, 6w7z – hUbc D2 + E3 ubiquitin-protein ligase LubX
    • 6w9d, 7ahz, 7ai0, 7ai1, 7r71 – hUbc D2 + E3 ubiquitin-protein ligase + Ub
    • 5v2w – hUbc D2 (mutant) + ubiquitin + TRIM23
    • 1ur6 – hUbc D2 + Cnot4 - NMR
    • 4auq, 6hpr – hUbc D2 (mutant) + baculoviral IAP repeat-containing protein + ubiquitin
    • 3jvz, 3jw0 – hUbc D2 (mutant) + E3 NEDD4-2 + ubiquitin
    • 6ttu – hUbc D2 in Cullin RING E3 ligase- Cryo EM
    • 3eb6 – fUbc D2 + baculoviral IAP repeat-containing protein- frog
  • Ubiquitin conjugating enzyme D3
    • 5egg, 1x23 – hUbc D3
    • 5ifr – hUbc D3 + ubiquitin
    • 2fuh – hUbc D3 + ubiquitin - NMR
    • 3ugb – hUbc D3 (mutant) + ubiquitin
    • 3l1z – hUbc D3 + ubiquitin conjugating factor
    • 4s3o, 3rpg – hUbc D3 + polycomb group ring finger protein + E3 ubiquitin-protein ligase RING2
    • 4bvu – hUbc D3 + OspG + ubiquitin
    • 6cp0 – hUbc D3 + SdcA
    • 6t7f – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2
    • 7jzv, 7lyb – hUbc D3 in nucleosome complex – Cryo EM
  • Ubiquitin conjugating enzyme E1
    • 3bzh – hUbc E1
    • 6fga – hUbc E1 + E3 TRIM21
  • Ubiquitin conjugating enzyme E2
    • 6w9a – hUbc E2 + E3 RLIM
  • Ubiquitin conjugating enzyme G1
    • 6d68 – hUbc G1 + ubiquitin
  • Ubiquitin conjugating enzyme G2
    • 2cyx – hUbc
    • 2kly – hUbc - NMR
    • 3fsh – hUbc + autocrine motility factor receptor
    • 2lxp – hUbc + AMFR peptide - NMR
    • 3h8k, 4lad – hUbc + AMFR peptide
    • 7lew – hUbc + AUP1 peptide
  • Ubiquitin conjugating enzyme H
  • Ubiquitin conjugating enzyme J2
  • Ubiquitin conjugating enzyme K
  • Ubiquitin conjugating enzyme Q1
  • Ubiquitin conjugating enzyme R1
    • 3rz3, 7m2k – hUbc + inhibitor
    • 4mdk – hUbc + ubiquitin + inhibitor
  • Ubiquitin conjugating enzyme R2
    • 6nyo – hUbc R2 + ubiquitin
  • Ubiquitin conjugating enzyme S
    • 1zdn – hUbc
    • 7ahf – hUbc (mutant)
    • 6qhk, 6s98 – hUbc catalytic domain
    • 6qh3, 6s96 – hUbc catalytic domain (mutant)
    • 5bnb – hUbc + ubiquitin
  • Ubiquitin conjugating enzyme T
    • 6r75 – hUbc T (mutant)
    • 4ccg – hUbc T + E3 ubiquitin-protein ligase Fancl
  • Ubiquitin conjugating enzyme Uev-1
    • 2a4d – hUbc catalytic domain
    • 2hlw – hUbc catalytic domain - NMR
    • 3e95 – PfUbc + ubiquitin carrier protein
  • Ubiquitin conjugating enzyme Z
  • Ubiquitin conjugating enzyme E2-18KDa
    • 6op8 – fyUbc + CUE domain-containing protein 4
  • Ubiquitin conjugating enzyme E2-25KDa (Huntington interacting protein 2 HIP-2)
    • 1yla, 2bep – hHIP-2
    • 3e46 – hHIP-2 (mutant)
    • 2bf8 – hHIP-2 + SUMO
    • 2o25 – hHIP-2 + Ubc9
    • 3f92 – hHIP-2/azorectase (mutant)
    • 3k9o, 3k9p – hHIP-2 + ubiquitin
  • Ubc E2-34KDa

}}

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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