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3roh

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==Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.==
==Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.==
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<StructureSection load='3roh' size='340' side='right' caption='[[3roh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='3roh' size='340' side='right'caption='[[3roh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ROH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ROH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMPREF0773_11197, lukE, lukEv, SAOUHSC_01955 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMPREF0773_11197, lukE, lukEv, SAOUHSC_01955 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3roh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3roh OCA], [http://pdbe.org/3roh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3roh RCSB], [http://www.ebi.ac.uk/pdbsum/3roh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3roh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3roh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3roh OCA], [https://pdbe.org/3roh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3roh RCSB], [https://www.ebi.ac.uk/pdbsum/3roh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3roh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LUKEV_STAA8 LUKEV_STAA8]] Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells. The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL). LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin.<ref>PMID:12636257</ref>
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[[https://www.uniprot.org/uniprot/LUKEV_STAA8 LUKEV_STAA8]] Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells. The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL). LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin.<ref>PMID:12636257</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Staa8]]
[[Category: Staa8]]
[[Category: Anderson, W F]]
[[Category: Anderson, W F]]

Revision as of 10:19, 22 June 2022

Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.

PDB ID 3roh

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