This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ryo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:30, 22 June 2022) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA==
==Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA==
-
<StructureSection load='3ryo' size='340' side='right' caption='[[3ryo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+
<StructureSection load='3ryo' size='340' side='right'caption='[[3ryo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ryo]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RYO FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ryo]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RYO FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sxn|3sxn]], [[3uy5|3uy5]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sxn|3sxn]], [[3uy5|3uy5]]</div></td></tr>
-
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eis, Rv2416c, MT2489, MTCY253.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eis, Rv2416c, MT2489, MTCY253.04 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ryo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ryo RCSB], [http://www.ebi.ac.uk/pdbsum/3ryo PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ryo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryo OCA], [https://pdbe.org/3ryo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ryo RCSB], [https://www.ebi.ac.uk/pdbsum/3ryo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ryo ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7.,Kim KH, An DR, Song J, Yoon JY, Kim HS, Yoon HJ, Im HN, Kim J, Kim do J, Lee SJ, Kim KH, Lee HM, Kim HJ, Jo EK, Lee JY, Suh SW Proc Natl Acad Sci U S A. 2012 May 15;109(20):7729-34. Epub 2012 Apr 30. PMID:22547814<ref>PMID:22547814</ref>
Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7.,Kim KH, An DR, Song J, Yoon JY, Kim HS, Yoon HJ, Im HN, Kim J, Kim do J, Lee SJ, Kim KH, Lee HM, Kim HJ, Jo EK, Lee JY, Suh SW Proc Natl Acad Sci U S A. 2012 May 15;109(20):7729-34. Epub 2012 Apr 30. PMID:22547814<ref>PMID:22547814</ref>
-
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3ryo" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Mycobacterium tuberculosis]]
+
[[Category: Large Structures]]
-
[[Category: An, D R.]]
+
[[Category: An, D R]]
-
[[Category: Im, H N.]]
+
[[Category: Im, H N]]
-
[[Category: Kim, D J.]]
+
[[Category: Kim, D J]]
-
[[Category: Kim, H J.]]
+
[[Category: Kim, H J]]
-
[[Category: Kim, H S.]]
+
[[Category: Kim, H S]]
-
[[Category: Kim, J.]]
+
[[Category: Kim, J]]
-
[[Category: Kim, K H.]]
+
[[Category: Kim, K H]]
-
[[Category: Lee, J Y.]]
+
[[Category: Lee, J Y]]
-
[[Category: Lee, S J.]]
+
[[Category: Lee, S J]]
-
[[Category: Song, J.]]
+
[[Category: Song, J]]
-
[[Category: Suh, S W.]]
+
[[Category: Suh, S W]]
-
[[Category: Yoon, H J.]]
+
[[Category: Yoon, H J]]
-
[[Category: Yoon, J Y.]]
+
[[Category: Yoon, J Y]]
[[Category: Acetyltransferase]]
[[Category: Acetyltransferase]]
[[Category: Gnat]]
[[Category: Gnat]]
[[Category: Transferase]]
[[Category: Transferase]]

Current revision

Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA

PDB ID 3ryo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ryo"
Personal tools