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3s45

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==wild-type HIV-2 protease with antiviral drug amprenavir==
==wild-type HIV-2 protease with antiviral drug amprenavir==
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<StructureSection load='3s45' size='340' side='right' caption='[[3s45]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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<StructureSection load='3s45' size='340' side='right'caption='[[3s45]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s45]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv2 9hiv2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S45 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv2 9hiv2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S45 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=478:{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC+ACID+TETRAHYDRO-FURAN-3-YL+ESTER'>478</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=478:{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC+ACID+TETRAHYDRO-FURAN-3-YL+ESTER'>478</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nu3|3nu3]], [[3ebz|3ebz]], [[3ecg|3ecg]], [[3ec0|3ec0]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3nu3|3nu3]], [[3ebz|3ebz]], [[3ecg|3ecg]], [[3ec0|3ec0]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11709 9HIV2])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11709 9HIV2])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-2_retropepsin HIV-2 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.47 3.4.23.47] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/HIV-2_retropepsin HIV-2 retropepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.47 3.4.23.47] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s45 OCA], [http://pdbe.org/3s45 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s45 RCSB], [http://www.ebi.ac.uk/pdbsum/3s45 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s45 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s45 OCA], [https://pdbe.org/3s45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s45 RCSB], [https://www.ebi.ac.uk/pdbsum/3s45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s45 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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</div>
</div>
<div class="pdbe-citations 3s45" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3s45" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: HIV-2 retropepsin]]
[[Category: HIV-2 retropepsin]]
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[[Category: Large Structures]]
[[Category: Tie, Y F]]
[[Category: Tie, Y F]]
[[Category: Wang, Y F]]
[[Category: Wang, Y F]]

Revision as of 10:37, 22 June 2022

wild-type HIV-2 protease with antiviral drug amprenavir

PDB ID 3s45

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