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3srk
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase== | |
| + | <StructureSection load='3srk' size='340' side='right'caption='[[3srk]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leime Leime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SRK FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pkl|1pkl]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5665 LEIME])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [https://pdbe.org/3srk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [https://www.ebi.ac.uk/pdbsum/3srk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3srk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Leime]] | ||
| + | [[Category: Pyruvate kinase]] | ||
| + | [[Category: Auld, D S]] | ||
| + | [[Category: Blackburn, E A]] | ||
| + | [[Category: Boxer, M]] | ||
| + | [[Category: Fothergill-Gilmore, L A]] | ||
| + | [[Category: McNae, I W]] | ||
| + | [[Category: Michels, P A.M]] | ||
| + | [[Category: Morgan, H P]] | ||
| + | [[Category: Shen, M]] | ||
| + | [[Category: Walkinshaw, M D]] | ||
| + | [[Category: Walsh, M]] | ||
| + | [[Category: Wear, M A]] | ||
| + | [[Category: Phosphenolpyruvate]] | ||
| + | [[Category: Phospho transfer]] | ||
| + | [[Category: Sugar kinase]] | ||
| + | [[Category: Tim barrel]] | ||
| + | [[Category: Transferase-inhibitor complex]] | ||
Current revision
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
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Categories: Large Structures | Leime | Pyruvate kinase | Auld, D S | Blackburn, E A | Boxer, M | Fothergill-Gilmore, L A | McNae, I W | Michels, P A.M | Morgan, H P | Shen, M | Walkinshaw, M D | Walsh, M | Wear, M A | Phosphenolpyruvate | Phospho transfer | Sugar kinase | Tim barrel | Transferase-inhibitor complex
