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3te6
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==Crystal Structure of the S. cerevisiae Sir3 AAA+ domain== | ==Crystal Structure of the S. cerevisiae Sir3 AAA+ domain== | ||
| - | <StructureSection load='3te6' size='340' side='right' caption='[[3te6]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='3te6' size='340' side='right'caption='[[3te6]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3te6]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3te6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TE6 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fvu|2fvu]], [[2fl7|2fl7]], [[1nyh|1nyh]], [[3owt|3owt]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fvu|2fvu]], [[2fl7|2fl7]], [[1nyh|1nyh]], [[3owt|3owt]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIR3, CMT1, MAR2, STE8, YLR442C, L9753.10 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIR3, CMT1, MAR2, STE8, YLR442C, L9753.10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3te6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3te6 OCA], [https://pdbe.org/3te6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3te6 RCSB], [https://www.ebi.ac.uk/pdbsum/3te6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3te6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SIR3_YEAST SIR3_YEAST]] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3te6" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Baker's yeast]] |
| + | [[Category: Large Structures]] | ||
[[Category: Hassler, M]] | [[Category: Hassler, M]] | ||
[[Category: Ladurner, A G]] | [[Category: Ladurner, A G]] | ||
Current revision
Crystal Structure of the S. cerevisiae Sir3 AAA+ domain
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Categories: Baker's yeast | Large Structures | Hassler, M | Ladurner, A G | Aaa+ domain | Gene regulation | Gene silencing | Heterochromatin | Hml | Hmr | Nucleus | Sir complex | Sir2 | Sir3 | Sir4 | Structural | Telomere
