This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3tfx
From Proteopedia
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3tfx.jpg|left|200px]] | ||
| - | + | ==Crystal structure of Orotidine 5'-phosphate decarboxylase from Lactobacillus acidophilus== | |
| - | + | <StructureSection load='3tfx' size='340' side='right'caption='[[3tfx]], [[Resolution|resolution]] 2.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_acidophilus"_moro_1900 "bacillus acidophilus" moro 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TFX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | --> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LBA1386, pyrF, pyrF/LBA1386 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1579 "Bacillus acidophilus" Moro 1900])</td></tr> |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tfx OCA], [https://pdbe.org/3tfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tfx RCSB], [https://www.ebi.ac.uk/pdbsum/3tfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tfx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PYRF_LACAC PYRF_LACAC]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity). | ||
| - | === | + | ==See Also== |
| - | + | *[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Bacillus acidophilus moro 1900]] |
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Chamala, S | + | [[Category: Chamala, S]] |
| - | [[Category: Evans, B | + | [[Category: Evans, B]] |
| - | [[Category: Foti, R | + | [[Category: Foti, R]] |
| - | [[Category: Gizzi, A | + | [[Category: Gizzi, A]] |
| - | [[Category: Hillerich, B | + | [[Category: Hillerich, B]] |
| - | [[Category: Kar, A | + | [[Category: Kar, A]] |
| - | [[Category: LaFleur, J | + | [[Category: LaFleur, J]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Satyanarayana, L | + | [[Category: Satyanarayana, L]] |
| - | [[Category: Seidel, R | + | [[Category: Seidel, R]] |
| - | [[Category: Swaminathan, S | + | [[Category: Swaminathan, S]] |
| - | [[Category: Villigas, G | + | [[Category: Villigas, G]] |
| - | [[Category: Zencheck, W | + | [[Category: Zencheck, W]] |
| - | + | ||
[[Category: Decarboxylase lyase]] | [[Category: Decarboxylase lyase]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
| - | [[Category: New york structural genomics research consortium]] | ||
[[Category: Nysgrc]] | [[Category: Nysgrc]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Pyrimidine metabolism]] | [[Category: Pyrimidine metabolism]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Tim barrel fold]] | [[Category: Tim barrel fold]] | ||
[[Category: Ump biosynthesis via de novo pathway]] | [[Category: Ump biosynthesis via de novo pathway]] | ||
[[Category: Ump from orotate]] | [[Category: Ump from orotate]] | ||
Current revision
Crystal structure of Orotidine 5'-phosphate decarboxylase from Lactobacillus acidophilus
| |||||||||||
Categories: Bacillus acidophilus moro 1900 | Large Structures | Orotidine-5'-phosphate decarboxylase | Almo, S C | Chamala, S | Evans, B | Foti, R | Gizzi, A | Hillerich, B | Kar, A | LaFleur, J | Structural genomic | Satyanarayana, L | Seidel, R | Swaminathan, S | Villigas, G | Zencheck, W | Decarboxylase lyase | Lyase | Nysgrc | Psi-biology | Pyrimidine metabolism | Tim barrel fold | Ump biosynthesis via de novo pathway | Ump from orotate
