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3ure

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==Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease==
==Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease==
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<StructureSection load='3ure' size='340' side='right' caption='[[3ure]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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<StructureSection load='3ure' size='340' side='right'caption='[[3ure]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ure]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysobacter_enzymogenes Lysobacter enzymogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3URE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3URE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ure]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_29487 Atcc 29487]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3URE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3URE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ssx|1ssx]], [[2alp|2alp]], [[4sgb|4sgb]], [[2oua|2oua]], [[2pfe|2pfe]], [[3urc|3urc]], [[3urd|3urd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ssx|1ssx]], [[2alp|2alp]], [[4sgb|4sgb]], [[2oua|2oua]], [[2pfe|2pfe]], [[3urc|3urc]], [[3urd|3urd]]</div></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alpha-LP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69 Lysobacter enzymogenes])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alpha-LP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69 ATCC 29487])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-lytic_endopeptidase Alpha-lytic endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.12 3.4.21.12] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-lytic_endopeptidase Alpha-lytic endopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.12 3.4.21.12] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ure FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ure OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ure RCSB], [http://www.ebi.ac.uk/pdbsum/3ure PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ure FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ure OCA], [https://pdbe.org/3ure PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ure RCSB], [https://www.ebi.ac.uk/pdbsum/3ure PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ure ProSAT]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Functional modulation of a protein folding landscape via side-chain distortion.,Kelch BA, Salimi NL, Agard DA Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9414-9. Epub 2012 May 25. PMID:22635267<ref>PMID:22635267</ref>
Functional modulation of a protein folding landscape via side-chain distortion.,Kelch BA, Salimi NL, Agard DA Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9414-9. Epub 2012 May 25. PMID:22635267<ref>PMID:22635267</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ure" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Alpha-lytic protease|Alpha-lytic protease]]
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*[[Alpha-lytic protease 3D structures|Alpha-lytic protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Alpha-lytic endopeptidase]]
[[Category: Alpha-lytic endopeptidase]]
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[[Category: Lysobacter enzymogenes]]
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[[Category: Atcc 29487]]
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[[Category: Agard, D A.]]
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[[Category: Large Structures]]
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[[Category: Kelch, B A.]]
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[[Category: Agard, D A]]
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[[Category: Kelch, B A]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Serine protease]]
[[Category: Serine protease]]

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Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease

PDB ID 3ure

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