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3v47
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| - | ==Crystal structure of the N- | + | |
| - | <StructureSection load='3v47' size='340' side='right' caption='[[3v47]], [[Resolution|resolution]] 2.47Å' scene=''> | + | ==Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin== |
| + | <StructureSection load='3v47' size='340' side='right'caption='[[3v47]], [[Resolution|resolution]] 2.47Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3v47]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3v47]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bdellostoma_burgeri Bdellostoma burgeri] and [https://en.wikipedia.org/wiki/Saldu Saldu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V47 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v44|3v44]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3v44|3v44]]</div></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fliC, fliC1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fliC, fliC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=98360 SALDU])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v47 OCA], [https://pdbe.org/3v47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v47 RCSB], [https://www.ebi.ac.uk/pdbsum/3v47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v47 ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/FLIC_SALDU FLIC_SALDU]] Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 17: | ||
Structural basis of TLR5-flagellin recognition and signaling.,Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA Science. 2012 Feb 17;335(6070):859-64. PMID:22344444<ref>PMID:22344444</ref> | Structural basis of TLR5-flagellin recognition and signaling.,Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA Science. 2012 Feb 17;335(6070):859-64. PMID:22344444<ref>PMID:22344444</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 3v47" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Flagellin|Flagellin]] | ||
| + | *[[Flagellin 3D structures|Flagellin 3D structures]] | ||
| + | *[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]] | ||
| + | *[[Variable lymphocyte receptor 3D structures|Variable lymphocyte receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bdellostoma burgeri]] | [[Category: Bdellostoma burgeri]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hong, H | + | [[Category: Saldu]] |
| - | [[Category: Wilson, I A | + | [[Category: Hong, H]] |
| - | [[Category: Yoon, S I | + | [[Category: Wilson, I A]] |
| + | [[Category: Yoon, S I]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Innate immune receptor]] | [[Category: Innate immune receptor]] | ||
[[Category: Innate immunity]] | [[Category: Innate immunity]] | ||
[[Category: Leucine-rich repeat]] | [[Category: Leucine-rich repeat]] | ||
Current revision
Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin
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