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3v80
From Proteopedia
(Difference between revisions)
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==Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with 5'-O-Propargylamino-5'-deoxyadenosine== | ==Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with 5'-O-Propargylamino-5'-deoxyadenosine== | ||
| - | <StructureSection load='3v80' size='340' side='right' caption='[[3v80]], [[Resolution|resolution]] 2.03Å' scene=''> | + | <StructureSection load='3v80' size='340' side='right'caption='[[3v80]], [[Resolution|resolution]] 2.03Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3v80]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3v80]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V80 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AOC:5-O-PROP-2-YN-1-YLADENOSINE'>AOC</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AOC:5-O-PROP-2-YN-1-YLADENOSINE'>AOC</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i2c|2i2c]], [[3v7v|3v7v]], [[3v7w|3v7w]], [[3v7y|3v7y]], [[3v8m|3v8m]], [[3v8n|3v8n]], [[3v8p|3v8p]], [[3v8q|3v8q]], [[3v8r|3v8r]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2i2c|2i2c]], [[3v7v|3v7v]], [[3v7w|3v7w]], [[3v7y|3v7y]], [[3v8m|3v8m]], [[3v8n|3v8n]], [[3v8p|3v8p]], [[3v8q|3v8q]], [[3v8r|3v8r]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ppnK1, lmo0968 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ppnK1, lmo0968 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 "Bacterium monocytogenes hominis" Nyfeldt 1932])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v80 OCA], [https://pdbe.org/3v80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v80 RCSB], [https://www.ebi.ac.uk/pdbsum/3v80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v80 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO]] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3v80" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3v80" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[NAD kinase|NAD kinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacterium monocytogenes hominis nyfeldt 1932]] | [[Category: Bacterium monocytogenes hominis nyfeldt 1932]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Assairi, L]] | [[Category: Assairi, L]] | ||
[[Category: Dugu, L]] | [[Category: Dugu, L]] | ||
Revision as of 08:38, 20 July 2022
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with 5'-O-Propargylamino-5'-deoxyadenosine
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Categories: Bacterium monocytogenes hominis nyfeldt 1932 | Large Structures | Assairi, L | Dugu, L | Dussurget, O | Gelin, M | Huteau, V | Labesse, G | Morellato, L | Pochet, S | Poncet-Montange, G | Inorganic polyphosphate/atp-nad kinase 1 | Ligand-screening by crystallography | Transferase | Two-domain kinase
