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3vhs

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Current revision (18:46, 27 July 2022) (edit) (undo)
 
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==Crystal structure of UBZ of human WRNIP1==
==Crystal structure of UBZ of human WRNIP1==
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<StructureSection load='3vhs' size='340' side='right' caption='[[3vhs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='3vhs' size='340' side='right'caption='[[3vhs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vhs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VHS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vhs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VHS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vht|3vht]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vht|3vht]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WRNIP1, WHIP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WRNIP1, WHIP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vhs OCA], [http://pdbe.org/3vhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vhs RCSB], [http://www.ebi.ac.uk/pdbsum/3vhs PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vhs OCA], [https://pdbe.org/3vhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vhs RCSB], [https://www.ebi.ac.uk/pdbsum/3vhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vhs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/WRIP1_HUMAN WRIP1_HUMAN]] Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.<ref>PMID:15670210</ref>
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[[https://www.uniprot.org/uniprot/WRIP1_HUMAN WRIP1_HUMAN]] Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.<ref>PMID:15670210</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Kawasaki, M]]
[[Category: Kawasaki, M]]
[[Category: Suzuki, N]]
[[Category: Suzuki, N]]

Current revision

Crystal structure of UBZ of human WRNIP1

PDB ID 3vhs

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