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3wgv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3wgv is ON HOLD Authors: Kanai, R., Ogawa, H., Vilsen, B., Cornelius, F., Toyoshima, C. Description: Crystal structure of a Na+-bound Na+,K+-ATPase...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin== | |
| + | <StructureSection load='3wgv' size='340' side='right'caption='[[3wgv]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3wgv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WGV FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=EFO:OLIGOMYCIN+A'>EFO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zxe|2zxe]], [[2zbd|2zbd]], [[3wgu|3wgu]]</div></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgv OCA], [https://pdbe.org/3wgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wgv RCSB], [https://www.ebi.ac.uk/pdbsum/3wgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wgv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/AT1B1_PIG AT1B1_PIG]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | ||
| - | + | ==See Also== | |
| - | + | *[[ATPase 3D structures|ATPase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sodium/potassium-exchanging ATPase]] | ||
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Cornelius, F]] | ||
| + | [[Category: Kanai, R]] | ||
| + | [[Category: Ogawa, H]] | ||
| + | [[Category: Toyoshima, C]] | ||
| + | [[Category: Vilsen, B]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Atpase]] | ||
| + | [[Category: Haloacid dehydrogenease superfamily]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-transport protein-antibiotic complex]] | ||
| + | [[Category: Ion pump]] | ||
| + | [[Category: Ion transport]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Na+ binding]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphate analogue]] | ||
| + | [[Category: Phosphoprotein]] | ||
Current revision
Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin
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Categories: Large Structures | Sodium/potassium-exchanging ATPase | Sus scrofa | Cornelius, F | Kanai, R | Ogawa, H | Toyoshima, C | Vilsen, B | Atp-binding | Atpase | Haloacid dehydrogenease superfamily | Hydrolase | Hydrolase-transport protein-antibiotic complex | Ion pump | Ion transport | Membrane protein | Na+ binding | Nucleotide-binding | Phosphate analogue | Phosphoprotein
