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2xq6
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xq6' size='340' side='right'caption='[[2xq6]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='2xq6' size='340' side='right'caption='[[2xq6]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xq6]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xq6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQ6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqa|2xqa]], [[2xq9|2xq9]], [[2xq7|2xq7]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xqa|2xqa]], [[2xq9|2xq9]], [[2xq7|2xq7]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq6 OCA], [https://pdbe.org/2xq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xq6 RCSB], [https://www.ebi.ac.uk/pdbsum/2xq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 05:25, 10 August 2022
Pentameric ligand gated ion channel GLIC in complex with cesium ion (Cs+)
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