This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3x00
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution== | ==Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution== | ||
| - | <StructureSection load='3x00' size='340' side='right' caption='[[3x00]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='3x00' size='340' side='right'caption='[[3x00]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3x00]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3x00]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X00 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDN:ETHANE-1,2-DIAMINE'>EDN</scene>, <scene name='pdbligand=ZOF:6-({5-[(2E,3AS,4S,6AR)-2-IMINOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANOYL}AMINO)HEXANOIC+ACID'>ZOF</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDN:ETHANE-1,2-DIAMINE'>EDN</scene>, <scene name='pdbligand=ZOF:6-({5-[(2E,3AS,4S,6AR)-2-IMINOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANOYL}AMINO)HEXANOIC+ACID'>ZOF</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wzn|3wzn]], [[3wzo|3wzo]], [[3wzp|3wzp]], [[3wzq|3wzq]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wzn|3wzn]], [[3wzo|3wzo]], [[3wzp|3wzp]], [[3wzq|3wzq]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x00 OCA], [https://pdbe.org/3x00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x00 RCSB], [https://www.ebi.ac.uk/pdbsum/3x00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x00 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 3x00" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3x00" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Avidin 3D structures|Avidin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 24: | Line 27: | ||
</StructureSection> | </StructureSection> | ||
[[Category: As 4 1583]] | [[Category: As 4 1583]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Doi, H]] | [[Category: Doi, H]] | ||
[[Category: Inoue, T]] | [[Category: Inoue, T]] | ||
Revision as of 05:37, 10 August 2022
Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution
| |||||||||||
Categories: As 4 1583 | Large Structures | Doi, H | Inoue, T | Kanai, M | Kawato, T | Kodama, T | Matsumura, H | Matsuoka, M | Meshizuka, T | Mizohata, E | Shimizu, Y | Sugiyama, A | Takasu, N | Yamamoto, T | Beta-barrel | Biotin binding protein
