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3x09
From Proteopedia
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==Crystal structure of PIP4KIIBETA F205L complex with AMP== | ==Crystal structure of PIP4KIIBETA F205L complex with AMP== | ||
| - | <StructureSection load='3x09' size='340' side='right' caption='[[3x09]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='3x09' size='340' side='right'caption='[[3x09]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3x09]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3x09]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X09 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wzz|3wzz]], [[3x01|3x01]], [[3x02|3x02]], [[3x03|3x03]], [[3x04|3x04]], [[3x05|3x05]], [[3x06|3x06]], [[3x07|3x07]], [[3x08|3x08]], [[3x0a|3x0a]], [[3x0b|3x0b]], [[3x0c|3x0c]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wzz|3wzz]], [[3x01|3x01]], [[3x02|3x02]], [[3x03|3x03]], [[3x04|3x04]], [[3x05|3x05]], [[3x06|3x06]], [[3x07|3x07]], [[3x08|3x08]], [[3x0a|3x0a]], [[3x0b|3x0b]], [[3x0c|3x0c]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x09 OCA], [https://pdbe.org/3x09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x09 RCSB], [https://www.ebi.ac.uk/pdbsum/3x09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x09 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]] | [[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Asara, J A]] | [[Category: Asara, J A]] | ||
[[Category: Cantley, L C]] | [[Category: Cantley, L C]] | ||
Revision as of 05:37, 10 August 2022
Crystal structure of PIP4KIIBETA F205L complex with AMP
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Categories: 1-phosphatidylinositol-5-phosphate 4-kinase | Human | Large Structures | Asara, J A | Cantley, L C | Daikoku, T | Dimitoris, A | Emerling, B | Ishida, T | Kahoud, E R | Lo, Y H | Locasale, J W | Sasaki, A T | Sasaki, M | Senda, M | Senda, T | Shimada, I | Sumita, K | Takano, T | Takeuchi, K | Terakawa, J | Yokota, T | Yoshino, H | Zhang, Y | Lipid kinase | Phosphoinositide signaling | Transferase
