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3x28
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Nitrile Hydratase mutant bR56K== | |
| + | <StructureSection load='3x28' size='340' side='right'caption='[[3x28]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3x28]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X28 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wvd|3wvd]], [[3wve|3wve]], [[3x20|3x20]], [[3x24|3x24]], [[3x25|3x25]], [[3x26|3x26]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nthA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928]), nthB, nha2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x28 OCA], [https://pdbe.org/3x28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x28 RCSB], [https://www.ebi.ac.uk/pdbsum/3x28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x28 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [[https://www.uniprot.org/uniprot/NHAB_RHOER NHAB_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. | ||
| - | + | ==See Also== | |
| - | + | *[[Nitrile hydratase|Nitrile hydratase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Mycobacterium erythropolis gray and thornton 1928]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nitrile hydratase]] | ||
| + | [[Category: Hashimoto, K]] | ||
| + | [[Category: Noguchi, K]] | ||
| + | [[Category: Odaka, M]] | ||
| + | [[Category: Yamanaka, Y]] | ||
| + | [[Category: Yohda, M]] | ||
| + | [[Category: Hydratase]] | ||
| + | [[Category: Lyase]] | ||
Current revision
Crystal structure of Nitrile Hydratase mutant bR56K
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