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3zdl

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==Vinculin head (1-258) in complex with a RIAM fragment==
==Vinculin head (1-258) in complex with a RIAM fragment==
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<StructureSection load='3zdl' size='340' side='right' caption='[[3zdl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3zdl' size='340' side='right'caption='[[3zdl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zdl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZDL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zdl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZDL FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zdl OCA], [http://pdbe.org/3zdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zdl RCSB], [http://www.ebi.ac.uk/pdbsum/3zdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zdl ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zdl OCA], [https://pdbe.org/3zdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zdl RCSB], [https://www.ebi.ac.uk/pdbsum/3zdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zdl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[http://www.uniprot.org/uniprot/AB1IP_HUMAN AB1IP_HUMAN]] Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.<ref>PMID:14530287</ref> <ref>PMID:15469846</ref>
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[[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[https://www.uniprot.org/uniprot/AB1IP_HUMAN AB1IP_HUMAN]] Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.<ref>PMID:14530287</ref> <ref>PMID:15469846</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Chick]]
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[[Category: Large Structures]]
[[Category: Barsukov, I L]]
[[Category: Barsukov, I L]]
[[Category: Bate, N]]
[[Category: Bate, N]]

Revision as of 05:42, 10 August 2022

Vinculin head (1-258) in complex with a RIAM fragment

PDB ID 3zdl

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