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3zfh

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==Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase==
==Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase==
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<StructureSection load='3zfh' size='340' side='right' caption='[[3zfh]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3zfh' size='340' side='right'caption='[[3zfh]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zfh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZFH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZFH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfh OCA], [http://pdbe.org/3zfh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zfh RCSB], [http://www.ebi.ac.uk/pdbsum/3zfh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfh OCA], [https://pdbe.org/3zfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zfh RCSB], [https://www.ebi.ac.uk/pdbsum/3zfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
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[[https://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Inosine monophosphate dehydrogenase|Inosine monophosphate dehydrogenase]]
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*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: IMP dehydrogenase]]
[[Category: IMP dehydrogenase]]
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[[Category: Large Structures]]
[[Category: Pseae]]
[[Category: Pseae]]
[[Category: Hunter, W N]]
[[Category: Hunter, W N]]

Revision as of 05:44, 10 August 2022

Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase

PDB ID 3zfh

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