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4a7h

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==Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)==
==Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)==
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<StructureSection load='4a7h' size='340' side='right' caption='[[4a7h]], [[Resolution|resolution]] 7.80&Aring;' scene=''>
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<SX load='4a7h' size='340' side='right' viewer='molstar' caption='[[4a7h]], [[Resolution|resolution]] 7.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4a7h]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11735 Atcc 11735], [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A7H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4a7h]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Dicdi Dicdi], [https://en.wikipedia.org/wiki/European_rabbit European rabbit] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A7H FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1alm|1alm]], [[1atn|1atn]], [[1eqy|1eqy]], [[1esv|1esv]], [[1h1v|1h1v]], [[1ijj|1ijj]], [[1j6z|1j6z]], [[1kxp|1kxp]], [[1lcu|1lcu]], [[1lkx|1lkx]], [[1lot|1lot]], [[1m8q|1m8q]], [[1ma9|1ma9]], [[1mvw|1mvw]], [[1nwk|1nwk]], [[1o18|1o18]], [[1o19|1o19]], [[1o1a|1o1a]], [[1o1b|1o1b]], [[1o1c|1o1c]], [[1o1d|1o1d]], [[1o1e|1o1e]], [[1o1f|1o1f]], [[1o1g|1o1g]], [[1p8z|1p8z]], [[1qz5|1qz5]], [[1qz6|1qz6]], [[1rdw|1rdw]], [[1rfq|1rfq]], [[1rgi|1rgi]], [[1s22|1s22]], [[1sqk|1sqk]], [[1t44|1t44]], [[1uy5|1uy5]], [[1wua|1wua]], [[1y64|1y64]], [[2a3z|2a3z]], [[2a40|2a40]], [[2a41|2a41]], [[2a42|2a42]], [[2a5x|2a5x]], [[2asm|2asm]], [[2aso|2aso]], [[2asp|2asp]], [[2d1k|2d1k]], [[2d3e|2d3e]], [[2ff3|2ff3]], [[2ff6|2ff6]], [[2fxu|2fxu]], [[2tma|2tma]], [[2v51|2v51]], [[2v52|2v52]], [[2vcp|2vcp]], [[2vyp|2vyp]], [[2w49|2w49]], [[2w4u|2w4u]], [[2y83|2y83]], [[2yje|2yje]], [[2yjf|2yjf]], [[4a7l|4a7l]], [[4a7n|4a7n]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1alm|1alm]], [[1atn|1atn]], [[1eqy|1eqy]], [[1esv|1esv]], [[1h1v|1h1v]], [[1ijj|1ijj]], [[1j6z|1j6z]], [[1kxp|1kxp]], [[1lcu|1lcu]], [[1lkx|1lkx]], [[1lot|1lot]], [[1m8q|1m8q]], [[1ma9|1ma9]], [[1mvw|1mvw]], [[1nwk|1nwk]], [[1o18|1o18]], [[1o19|1o19]], [[1o1a|1o1a]], [[1o1b|1o1b]], [[1o1c|1o1c]], [[1o1d|1o1d]], [[1o1e|1o1e]], [[1o1f|1o1f]], [[1o1g|1o1g]], [[1p8z|1p8z]], [[1qz5|1qz5]], [[1qz6|1qz6]], [[1rdw|1rdw]], [[1rfq|1rfq]], [[1rgi|1rgi]], [[1s22|1s22]], [[1sqk|1sqk]], [[1t44|1t44]], [[1uy5|1uy5]], [[1wua|1wua]], [[1y64|1y64]], [[2a3z|2a3z]], [[2a40|2a40]], [[2a41|2a41]], [[2a42|2a42]], [[2a5x|2a5x]], [[2asm|2asm]], [[2aso|2aso]], [[2asp|2asp]], [[2d1k|2d1k]], [[2d3e|2d3e]], [[2ff3|2ff3]], [[2ff6|2ff6]], [[2fxu|2fxu]], [[2tma|2tma]], [[2v51|2v51]], [[2v52|2v52]], [[2vcp|2vcp]], [[2vyp|2vyp]], [[2w49|2w49]], [[2w4u|2w4u]], [[2y83|2y83]], [[2yje|2yje]], [[2yjf|2yjf]], [[4a7l|4a7l]], [[4a7n|4a7n]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7h OCA], [http://pdbe.org/4a7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a7h RCSB], [http://www.ebi.ac.uk/pdbsum/4a7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7h ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7h OCA], [https://pdbe.org/4a7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a7h RCSB], [https://www.ebi.ac.uk/pdbsum/4a7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/MYOE_DICDI MYOE_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. May play a role in moving membranes relative to actin. [[http://www.uniprot.org/uniprot/TPM1_RABIT TPM1_RABIT]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
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[[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[https://www.uniprot.org/uniprot/MYOE_DICDI MYOE_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. May play a role in moving membranes relative to actin. [[https://www.uniprot.org/uniprot/TPM1_RABIT TPM1_RABIT]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Actin|Actin]]
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*[[Actin 3D structures|Actin 3D structures]]
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*[[Myosin|Myosin]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
*[[Tropomyosin|Tropomyosin]]
*[[Tropomyosin|Tropomyosin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Atcc 11735]]
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[[Category: Dicdi]]
[[Category: European rabbit]]
[[Category: European rabbit]]
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[[Category: Large Structures]]
[[Category: Myosin ATPase]]
[[Category: Myosin ATPase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]

Current revision

Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)

4a7h, resolution 7.80Å

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