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4afi

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<StructureSection load='4afi' size='340' side='right'caption='[[4afi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4afi' size='340' side='right'caption='[[4afi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4afi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AFI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4afi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AFI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PR:PRASEODYMIUM+ION'>PR</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PR:PRASEODYMIUM+ION'>PR</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vx8|2vx8]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vx8|2vx8]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4afi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afi OCA], [http://pdbe.org/4afi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4afi RCSB], [http://www.ebi.ac.uk/pdbsum/4afi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4afi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4afi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afi OCA], [https://pdbe.org/4afi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4afi RCSB], [https://www.ebi.ac.uk/pdbsum/4afi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4afi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AP3D1_HUMAN AP3D1_HUMAN]] Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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[[https://www.uniprot.org/uniprot/AP3D1_HUMAN AP3D1_HUMAN]] Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Evans, P R]]
[[Category: Evans, P R]]
[[Category: Kent, H M]]
[[Category: Kent, H M]]

Revision as of 05:32, 25 August 2022

Complex between Vamp7 longin domain and fragment of delta-adaptin from AP3

PDB ID 4afi

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