This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4al8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:37, 25 August 2022) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of Dengue virus DIII in complex with Fab 2H12==
==Structure of Dengue virus DIII in complex with Fab 2H12==
-
<StructureSection load='4al8' size='340' side='right' caption='[[4al8]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
+
<StructureSection load='4al8' size='340' side='right'caption='[[4al8]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4al8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AL8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4al8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AL8 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ala|4ala]], [[4am0|4am0]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ala|4ala]], [[4am0|4am0]]</div></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4al8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4al8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4al8 RCSB], [http://www.ebi.ac.uk/pdbsum/4al8 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4al8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4al8 OCA], [https://pdbe.org/4al8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4al8 RCSB], [https://www.ebi.ac.uk/pdbsum/4al8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4al8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/Q8BE57_9FLAV Q8BE57_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
+
[[https://www.uniprot.org/uniprot/Q8BE57_9FLAV Q8BE57_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4al8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
Line 23: Line 25:
[[Category: Dengue virus]]
[[Category: Dengue virus]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
[[Category: Flanagan, A]]
[[Category: Flanagan, A]]
[[Category: Grimes, J M]]
[[Category: Grimes, J M]]

Current revision

Structure of Dengue virus DIII in complex with Fab 2H12

PDB ID 4al8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4al8"
Personal tools