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7y9u
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the NPA-bound state== | |
| - | + | <StructureSection load='7y9u' size='340' side='right'caption='[[7y9u]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7y9u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y9U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E7O:2-(naphthalen-1-ylcarbamoyl)benzoic+acid'>E7O</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y9u OCA], [https://pdbe.org/7y9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y9u RCSB], [https://www.ebi.ac.uk/pdbsum/7y9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y9u ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PINI_ARATH PINI_ARATH]] Acts as a component of the auxin efflux carrier. Seems to be involved in the basipetal auxin transport. Mediates the formation of auxin gradient which is required to ensure correct organogenesis. Coordinated polar localization of PIN1 is directly regulated by the vesicle trafficking process and apical-basal PIN1 polarity also depends on the phosphorylation of conserved serine residues by PID kinase. The ARF-GEF protein GNOM is required for the correct recycling of PIN1 between the plasma membrane and endosomal compartments.<ref>PMID:14651850</ref> <ref>PMID:20407025</ref> <ref>PMID:20439545</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu X]] | ||
| + | [[Category: Sun L]] | ||
| + | [[Category: Xia J]] | ||
| + | [[Category: Yang Z]] | ||
Current revision
Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the NPA-bound state
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