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4bsu
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4bsu is ON HOLD Authors: Peng, W.C., de Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P. Description: Structure of the ect...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form== | |
| - | + | <StructureSection load='4bsu' size='340' side='right'caption='[[4bsu]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4bsu]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BSU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bsu OCA], [https://pdbe.org/4bsu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bsu RCSB], [https://www.ebi.ac.uk/pdbsum/4bsu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bsu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/LGR5_HUMAN LGR5_HUMAN]] Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Clevers H]] | ||
| + | [[Category: Forneris F]] | ||
| + | [[Category: Granneman JCM]] | ||
| + | [[Category: Gros P]] | ||
| + | [[Category: Huch M]] | ||
| + | [[Category: Peng WC]] | ||
| + | [[Category: De Lau W]] | ||
Current revision
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
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Categories: Homo sapiens | Large Structures | Clevers H | Forneris F | Granneman JCM | Gros P | Huch M | Peng WC | De Lau W
