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4bub

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{{STRUCTURE_4bub| PDB=4bub | SCENE= }}
 
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===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP===
 
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{{ABSTRACT_PUBMED_23826965}}
 
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==About this Structure==
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==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==
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[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA].
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<StructureSection load='4bub' size='340' side='right'caption='[[4bub]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BUB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [https://pdbe.org/4bub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [https://www.ebi.ac.uk/pdbsum/4bub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>
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==Reference==
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==See Also==
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<ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/>
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*[[Mur ligase|Mur ligase]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Contreras-Martel, C.]]
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[[Category: Contreras-Martel C]]
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[[Category: Dessen, A.]]
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[[Category: Dessen A]]
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[[Category: Favini-Stabile, S.]]
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[[Category: Favini-Stabile S]]
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[[Category: Thielens, N.]]
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[[Category: Thielens N]]
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[[Category: Adp-forming enzyme]]
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[[Category: Atp- binding]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Cell shape]]
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[[Category: Cell wall]]
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[[Category: Ligase]]
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[[Category: Mure]]
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[[Category: Nucleotide-binding]]
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[[Category: Peptidoglycan synthesis]]
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Current revision

CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP

PDB ID 4bub

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