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4c2c
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4c2c is ON HOLD until Paper Publication Authors: Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T. Description: Crystal structure of the protease C...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the protease CtpB in an active state== | |
| - | + | <StructureSection load='4c2c' size='340' side='right'caption='[[4c2c]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4c2c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168] and [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C2C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c2c OCA], [https://pdbe.org/4c2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c2c RCSB], [https://www.ebi.ac.uk/pdbsum/4c2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c2c ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/CTPB_BACSU CTPB_BACSU]] Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation.<ref>PMID:14526016</ref> <ref>PMID:16818230</ref> <ref>PMID:17557826</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus subtilis subsp. subtilis str. 168]] | ||
| + | [[Category: Escherichia coli BL21]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Clausen T]] | ||
| + | [[Category: Heuck A]] | ||
| + | [[Category: Kurzbauer R]] | ||
| + | [[Category: Mastny M]] | ||
Current revision
Crystal structure of the protease CtpB in an active state
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