This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4c2c
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4c2c| PDB=4c2c | SCENE= }} | ||
| - | ===Crystal structure of the protease CtpB in an active state=== | ||
| - | {{ABSTRACT_PUBMED_24243021}} | ||
| - | == | + | ==Crystal structure of the protease CtpB in an active state== |
| - | [[ | + | <StructureSection load='4c2c' size='340' side='right'caption='[[4c2c]], [[Resolution|resolution]] 1.90Å' scene=''> |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4c2c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168] and [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C2C FirstGlance]. <br> | |
| - | [[4c2c]] is a 3 chain structure with sequence from [ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c2c OCA], [https://pdbe.org/4c2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c2c RCSB], [https://www.ebi.ac.uk/pdbsum/4c2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c2c ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| - | [[ | + | [[https://www.uniprot.org/uniprot/CTPB_BACSU CTPB_BACSU]] Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation.<ref>PMID:14526016</ref> <ref>PMID:16818230</ref> <ref>PMID:17557826</ref> |
| - | [ | + | == References == |
| - | [ | + | <references/> |
| - | [[ | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bacillus subtilis subsp. subtilis str. 168]] |
| - | [[Category: | + | [[Category: Escherichia coli BL21]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Clausen T]] |
| - | [[Category: | + | [[Category: Heuck A]] |
| - | [[Category: | + | [[Category: Kurzbauer R]] |
| + | [[Category: Mastny M]] | ||
Current revision
Crystal structure of the protease CtpB in an active state
| |||||||||||
