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4c3q
From Proteopedia
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==Neutron structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB) at 100K== | ==Neutron structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB) at 100K== | ||
| - | <StructureSection load='4c3q' size='340' side='right' caption='[[4c3q]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4c3q' size='340' side='right'caption='[[4c3q]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4c3q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3Q OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4c3q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C3Q FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BZB:BENZO[B]THIOPHENE-2-BORONIC+ACID'>BZB</scene>, <scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BZB:BENZO[B]THIOPHENE-2-BORONIC+ACID'>BZB</scene>, <scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c3q OCA], [https://pdbe.org/4c3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c3q RCSB], [https://www.ebi.ac.uk/pdbsum/4c3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c3q ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity. | ||
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| + | ==See Also== | ||
| + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli BL21]] |
| - | [[Category: Coates | + | [[Category: Large Structures]] |
| - | [[Category: Ng | + | [[Category: Coates L]] |
| - | [[Category: Ostermann | + | [[Category: Ng JD]] |
| - | [[Category: Schrader | + | [[Category: Ostermann A]] |
| - | [[Category: Tomanicek | + | [[Category: Schrader T]] |
| - | [[Category: Weiss | + | [[Category: Tomanicek SJ]] |
| - | + | [[Category: Weiss KL]] | |
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Current revision
Neutron structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB) at 100K
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