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7s15
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==GLP-1 receptor bound with Pfizer small molecule agonist== | |
| - | + | <StructureSection load='7s15' size='340' side='right'caption='[[7s15]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7s15]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S15 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=82L:2-[(4-{6-[(2,4-difluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(1-ethyl-1H-imidazol-5-yl)methyl]-1H-benzimidazole-6-carboxylic+acid'>82L</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s15 OCA], [https://pdbe.org/7s15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s15 RCSB], [https://www.ebi.ac.uk/pdbsum/7s15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s15 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dias JM]] | ||
| + | [[Category: Han S]] | ||
| + | [[Category: Liu Y]] | ||
Current revision
GLP-1 receptor bound with Pfizer small molecule agonist
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Categories: Homo sapiens | Large Structures | Dias JM | Han S | Liu Y
