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7ssg

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'''Unreleased structure'''
 
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The entry 7ssg is ON HOLD until Paper Publication
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==Mfd DNA complex==
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<StructureSection load='7ssg' size='340' side='right'caption='[[7ssg]], [[Resolution|resolution]] 5.20&Aring;' scene=''>
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Authors: Oakley, A.J., Xu, Z.-Q.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ssg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SSG FirstGlance]. <br>
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Description: Mfd DNA complex
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ssg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ssg OCA], [https://pdbe.org/7ssg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ssg RCSB], [https://www.ebi.ac.uk/pdbsum/7ssg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ssg ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Xu, Z.-Q]]
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== Function ==
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[[Category: Oakley, A.J]]
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[[https://www.uniprot.org/uniprot/MFD_ECOLI MFD_ECOLI]] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site. Can also dissociate RNAP that is blocked by low concentration of nucleoside triphosphates or by physical obstruction, such as bound proteins. In addition, can rescue arrested complexes by promoting forward translocation. Has ATPase activity, which is required for removal of stalled RNAP, but seems to lack helicase activity. May act through a translocase activity that rewinds upstream DNA, leading either to translocation or to release of RNAP when the enzyme active site can not continue elongation.<ref>PMID:8465200</ref> <ref>PMID:7876261</ref> <ref>PMID:7876262</ref> <ref>PMID:12086674</ref> <ref>PMID:19700770</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Oakley AJ]]
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[[Category: Xu Z-Q]]

Current revision

Mfd DNA complex

PDB ID 7ssg

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