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7xmv

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==E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P==
==E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P==
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<StructureSection load='7xmv' size='340' side='right'caption='[[7xmv]]' scene=''>
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<StructureSection load='7xmv' size='340' side='right'caption='[[7xmv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XMV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7xmv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MG1655 Escherichia coli str. K-12 substr. MG1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XMV FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xmv OCA], [https://pdbe.org/7xmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xmv RCSB], [https://www.ebi.ac.uk/pdbsum/7xmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xmv ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=HSX:5-O-PHOSPHONO-ALPHA-D-RIBOFURANOSE'>HSX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xmv OCA], [https://pdbe.org/7xmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xmv RCSB], [https://www.ebi.ac.uk/pdbsum/7xmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xmv ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/KPRS_ECOLI KPRS_ECOLI]] Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).[HAMAP-Rule:MF_00583]<ref>PMID:10954724</ref> <ref>PMID:2542328</ref> <ref>PMID:3009477</ref> <ref>PMID:6290219</ref> <ref>PMID:7657655</ref> <ref>PMID:8679571</ref> <ref>PMID:9125530</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli str. K-12 substr. MG1655]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hu, HH, Lu, GM, Chang, CC]]
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[[Category: Chang CC]]
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[[Category: Hu HH]]
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[[Category: Liu JL]]
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[[Category: Lu GM]]

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E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P

PDB ID 7xmv

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